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HFE 抗体 (N-Term)

This anti-HFE antibody is a 兔 多克隆 antibody detecting HFE in WB. Suitable for 人, 小鼠, 大鼠, Cow, 马 和 兔.
产品编号 ABIN2781799
发货至: 中国
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Quick Overview for HFE 抗体 (N-Term) (ABIN2781799)

抗原

See all HFE 抗体
HFE (Hemochromatosis (HFE))

适用

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人, 小鼠, 大鼠, Cow, 马, 兔

宿主

  • 48
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克隆类型

  • 49
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多克隆

标记

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This HFE antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    MGASEQDLGL SLFEALGYVD DQLFVFYDHE SRRVEPRTPW VSSRISSQMW

    预测反应

    Cow: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 79%

    产品特性

    This is a rabbit polyclonal antibody against HFE. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human HFE
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 348 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    HFE (Hemochromatosis (HFE))

    别名

    HFE

    背景

    HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.
    Alias Symbols: HFE1, HH, HLA-H, MGC103790, dJ221C16.10.1, MVCD7, TFQTL2
    Protein Interaction Partner: B2M, SYVN1, UBC, TFR2, TFRC,
    Protein Size: 348

    分子量

    40 kDa

    基因ID

    3077

    NCBI登录号

    NM_000410, NP_000401

    UniProt

    Q30201

    途径

    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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