NAT2 抗体 (Middle Region)
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北京 101111
Quick Overview for NAT2 抗体 (Middle Region) (ABIN310568)
抗原
See all NAT2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- CLTEERGIWY LDQIRREQYI TNKEFLNSHL LPKKKHQKIY LFTLEPRTIE
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特异性
- Antibody reacts with both NAT1 and NAT2
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against NAT2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human NAT2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 290 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Stent-graft repair for thoracic aortic disease: results of an independent nationwide study in France from 1999 to 2001." in: The Journal of thoracic and cardiovascular surgery, Vol. 131, Issue 1, pp. 131-7, (2006) (PubMed).
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- NAT2 (N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2))
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别名
- NAT2
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背景
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NAT2 is a N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in its gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity.This gene encodes N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near NAT2.
Alias Symbols: AAC2, PNAT
Protein Interaction Partner: APP, NAA10,
Protein Size: 290 -
分子量
- 32 kDa
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基因ID
- 10
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NCBI登录号
- NM_000015, NP_000006
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UniProt
- P11245
抗原
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