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NAT2 抗体 (Middle Region)

There is 1 publication for this product available. The 兔 多克隆 anti-NAT2 antibody is suitable to detect NAT2 in samples from 人. It has been validated for WB.
产品编号 ABIN2781757
发货至: 中国
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Quick Overview for NAT2 抗体 (Middle Region) (ABIN2781757)

抗原

See all NAT2 抗体
NAT2 (N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2))

适用

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宿主

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克隆类型

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多克隆

标记

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This NAT2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    CLTEERGIWY LDQIRREQYI TNKEFLNSHL LPKKKHQKIY LFTLEPRTIE

    特异性

    Antibody reacts with both NAT1 and NAT2

    预测反应

    Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against NAT2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human NAT2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 290 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ricco, Cau, Marchand, Marty, Rodde-Dunet, Fender, Allemand, Corsini: "Stent-graft repair for thoracic aortic disease: results of an independent nationwide study in France from 1999 to 2001." in: The Journal of thoracic and cardiovascular surgery, Vol. 131, Issue 1, pp. 131-7, (2006) (PubMed).

  • 抗原

    NAT2 (N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2))

    别名

    NAT2

    背景

    NAT2 is a N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in its gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity.This gene encodes N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near NAT2.
    Alias Symbols: AAC2, PNAT
    Protein Interaction Partner: APP, NAA10,
    Protein Size: 290

    分子量

    32 kDa

    基因ID

    10

    NCBI登录号

    NM_000015, NP_000006

    UniProt

    P11245
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