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ChT 抗体 (C-Term)

This anti-ChT antibody is a 兔 多克隆 antibody detecting ChT in WB. Suitable for 小鼠, 人, 大鼠, Cow, 豚鼠, 兔, 犬 和 马.
产品编号 ABIN2781677
发货至: 中国

Quick Overview for ChT 抗体 (C-Term) (ABIN2781677)

抗原

See all ChT 抗体
ChT (High Affinity Choline Transporter (ChT))

适用

  • 10
  • 10
  • 10
  • 9
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
小鼠, 人, 大鼠, Cow, 豚鼠, 兔, 犬, 马

宿主

  • 11
  • 10

克隆类型

  • 11
  • 10
多克隆

标记

  • 15
  • 2
  • 2
  • 2
This ChT antibody is un-conjugated

应用范围

  • 12
  • 9
  • 7
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    ILVKNENIKL DELALVKPRQ SMTLSSTFTN KEAFLDVDSS PEGSGTEDNL

    预测反应

    Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against SLC5A7. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of human SLC5A7
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    ChT (High Affinity Choline Transporter (ChT))

    别名

    SLC5A7

    背景

    This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants.
    Alias Symbols: CHT, CHT1, HMN7A
    Protein Size: 475

    分子量

    52 kDa

    基因ID

    60482

    NCBI登录号

    NM_001305005, NP_001291934

    UniProt

    Q9GZV3
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