ORCTL-2/SLC22A18 抗体 (N-Term)
Quick Overview for ORCTL-2/SLC22A18 抗体 (N-Term) (ABIN2781574)
抗原
See all ORCTL-2/SLC22A18 (SLC22A18) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- AASSPALPGV YLLFASRLPG ALMHTLPAAQ MVITDLSAPE ERPAALGRLG
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预测反应
- Cow: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against SLC22A18. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SLC22A18
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 424 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ORCTL-2/SLC22A18 (SLC22A18) (Solute Carrier Family 22 Member 18 (SLC22A18))
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别名
- SLC22A18
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背景
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This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region as well as the transport of chloroquine- and quinidine-related compounds in the kidney.This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region as well as the transport of chloroquine- and quinidine-related compounds in the kidney. Two alternative transcripts encoding the same isoform have been described.
Alias Symbols: BWR1A, BWSCR1A, DKFZp667A184, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5, p45-BWR1A
Protein Interaction Partner: RNF167, UBC,
Protein Size: 424 -
分子量
- 45 kDa
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基因ID
- 5002
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NCBI登录号
- NM_002555, NP_002546
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UniProt
- Q96BI1
抗原
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