CCL17 抗体 (N-Term)
Quick Overview for CCL17 抗体 (N-Term) (ABIN2781510)
抗原
See all CCL17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- FIIKLIKWLM IAIPATFVNS AIRYLECKLA LAFRTRLVDH AYETYFTNQT
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against ABCD2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ABCD2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 740 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))
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别名
- ABCD2
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背景
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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown, however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis.
Alias Symbols: ABC39, ALDL1, ALDR, ALDRP, hALDR
Protein Interaction Partner: UBC, PXA1, PXA2, ABCD2, PEX19, ABCD1, ABCD3,
Protein Size: 740 -
分子量
- 83 kDa
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基因ID
- 225
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NCBI登录号
- NM_005164, NP_005155
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UniProt
- Q9UBJ2
抗原
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