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MTTP 抗体 (N-Term)

This anti-MTTP antibody is a 兔 多克隆 antibody detecting MTTP in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 和 兔. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN2781495
发货至: 中国

Quick Overview for MTTP 抗体 (N-Term) (ABIN2781495)

抗原

See all MTTP 抗体
MTTP (Microsomal Triglyceride Transfer Protein (MTTP))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔

宿主

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克隆类型

  • 32
多克隆

标记

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This MTTP antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    MILLAVLFLC FISSYSASVK GHTTGLSLNN DRLYKLTYST EVLLDRGKGK

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against MTTP. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human MTTP
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 894 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lee, Bao, Ishikawa, Wang, Lim: "Cardiomyocyte Regulation of Systemic Lipid Metabolism by the Apolipoprotein B-Containing Lipoproteins in Drosophila." in: PLoS genetics, Vol. 13, Issue 1, pp. e1006555, (2017) (PubMed).

    Ward, Dail, Chambers: "In Vitro effect of DDE exposure on the regulation of lipid metabolism and secretion in McA-RH7777 hepatocytes: A potential role in dyslipidemia which may increase the risk of type 2 diabetes mellitus." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 37, pp. 9-14, (2016) (PubMed).

    Lundahl, Skoglund-Andersson, Caslake, Bedford, Stewart, Hamsten, Packard, Karpe: "Microsomal triglyceride transfer protein -493T variant reduces IDL plus LDL apoB production and the plasma concentration of large LDL particles." in: American journal of physiology. Endocrinology and metabolism, Vol. 290, Issue 4, pp. E739-45, (2006) (PubMed).

  • 抗原

    MTTP (Microsomal Triglyceride Transfer Protein (MTTP))

    别名

    MTTP

    背景

    MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.
    Alias Symbols: ABL, MGC149819, MGC149820, MTP
    Protein Interaction Partner: HSP90B1, APOB,
    Protein Size: 894

    分子量

    97 kDa

    基因ID

    4547

    NCBI登录号

    NM_000253, NP_000244

    UniProt

    P55157

    途径

    Transition Metal Ion Homeostasis
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