CPB2 抗体 (Middle Region)
Quick Overview for CPB2 抗体 (Middle Region) (ABIN2781326)
抗原
See all CPB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- RSKSKDHEEL SLVASEAVRA IEKTSKNTRY THGHGSETLY LAPGGGDDWI
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预测反应
- Dog: 86%, Guinea Pig: 83%, Horse: 85%, Human: 100%, Mouse: 92%, Rabbit: 83%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against CPB2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CPB2
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anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 113-422) antibody
CPB2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 138-386) antibodyCPB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 187-327) antibodyCPB2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 225-372) antibodyCPB2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 164-417) antibodyCPB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 1-423) antibodyCPB2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 1-423) antibodyCPB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 166-388) antibodyCPB2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 324-373) antibodyCPB2 适用: 人, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 165-387) antibodyCPB2 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 423 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
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别名
- CPB2
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背景
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Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms.
Alias Symbols: CPU, PCPB, TAFI
Protein Interaction Partner: FN1, TINAG, UBC, PZP, F2, PLG, C5, A2M,
Protein Size: 423 -
分子量
- 36 kDa
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基因ID
- 1361
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NCBI登录号
- NM_001872, NP_001863
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UniProt
- Q96IY4
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途径
- Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis
抗原
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