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GLS2 抗体 (Middle Region)

Cited in 2+ publications. This 兔 多克隆 anti-GLS2 antibody specifically detects GLS2 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, 犬, 马, Pig, 斑马鱼, Cow, 豚鼠 和 兔 samples.
产品编号 ABIN2781319
发货至: 中国
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Quick Overview for GLS2 抗体 (Middle Region) (ABIN2781319)

抗原

See all GLS2 抗体
GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))

适用

人, 小鼠, 大鼠, 犬, 马, Pig, 斑马鱼, Cow, 豚鼠, 兔

宿主

  • 37
  • 4

克隆类型

  • 37
  • 4
多克隆

标记

  • 18
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GLS2 antibody is un-conjugated

应用范围

  • 20
  • 19
  • 13
  • 13
  • 10
  • 8
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    FVGKEPSGLR YNKLSLNEEG IPHNPMVNAG AIVVSSLIKM DCNKAEKFDF

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

    产品特性

    This is a rabbit polyclonal antibody against GLS2. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human GLS2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 327 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

    Toriumi, Mouri, Narusawa, Aoyama, Ikawa, Lu, Nagai, Mamiya, Kim, Nabeshima: "Prenatal NMDA receptor antagonism impaired proliferation of neuronal progenitor, leading to fewer glutamatergic neurons in the prefrontal cortex." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 37, Issue 6, pp. 1387-96, (2012) (PubMed).

  • 抗原

    GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))

    别名

    GLS2

    背景

    GLS2 is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. This protein is functionally similar to the kidney glutaminase but is a little smaller in size. Originally thought to be liver-specific, this protein has been found in other tissues as well.
    Alias Symbols: GA, GLS, LGA, MGC71567, hLGA
    Protein Interaction Partner: SNTA1, GRHPR, TAX1BP3, PAG1, DLG2, INADL, DLG4, RGS3, DLG1, DLG3, CASK,
    Protein Size: 327

    分子量

    36 kDa

    基因ID

    27165

    NCBI登录号

    NM_013267

    UniProt

    Q9UI32

    途径

    Dicarboxylic Acid Transport, Warburg Effect
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