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ECH1 抗体 (N-Term)

This anti-ECH1 antibody is a 兔 多克隆 antibody detecting ECH1 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 豚鼠, 兔 和 犬. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN2781318
发货至: 中国

Quick Overview for ECH1 抗体 (N-Term) (ABIN2781318)

抗原

See all ECH1 抗体
ECH1 (Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1))

适用

  • 28
  • 19
  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, Cow, 豚鼠, 兔, 犬

宿主

  • 40
  • 3

克隆类型

  • 41
  • 2
多克隆

标记

  • 20
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ECH1 antibody is un-conjugated

应用范围

  • 37
  • 20
  • 13
  • 13
  • 9
  • 4
  • 4
  • 4
  • 3
  • 3
Western Blotting (WB)
  • 抗原表位

    • 16
    • 8
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    N-Term

    序列

    PDHSYESLRV TSAQKHVLHV QLNRPNKRNA MNKVFWREMV ECFNKISRDA

    预测反应

    Cow: 100%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against ECH1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human ECH1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 328 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Xie, Zhang, Lei, Ouyang, Du: "Ananas comosus L. Leaf Phenols and p-Coumaric Acid Regulate Liver Fat Metabolism by Upregulating CPT-1 Expression." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 903258, (2014) (PubMed).

    Xie, Wang, Zhang, Li, Can, Qing, Kung, Zhang: "Enhanced peroxisomal ?-oxidation metabolism in visceral adipose tissues of high-fat diet-fed obesity-resistant C57BL/6 mice." in: Experimental and therapeutic medicine, Vol. 2, Issue 2, pp. 309-315, (2012) (PubMed).

  • 抗原

    ECH1 (Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1))

    别名

    ECH1

    背景

    ECH1 is a member of the hydratase/isomerase superfamily. ECH1 shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The protein contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway.This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.
    Alias Symbols: HPXEL
    Protein Interaction Partner: FAM9B, HUWE1, TRAF1, UBC, MDM2, PPP6R3, IQCB1, STAT3, PEX5, EEF1D, DNAJB11, HNRNPUL1, OPA1, APP, HTT, EEF1G, HDAC5, ICT1, TLR10, PAFAH1B3, SERPINB9, CSTF2, TIMP1,
    Protein Size: 328

    分子量

    36 kDa

    基因ID

    1891

    NCBI登录号

    NM_001398, NP_001389

    UniProt

    Q13011

    途径

    Monocarboxylic Acid Catabolic Process
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