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GCDH 抗体 (C-Term)

This anti-GCDH antibody is a 兔 多克隆 antibody detecting GCDH in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 斑马鱼, 兔, 犬, 马 和 Pig. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN2781317
发货至: 中国

Quick Overview for GCDH 抗体 (C-Term) (ABIN2781317)

抗原

See all GCDH 抗体
GCDH (Glutaryl-CoA Dehydrogenase (GCDH))

适用

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人, 小鼠, 大鼠, 斑马鱼, 兔, 犬, 马, Pig

宿主

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克隆类型

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多克隆

标记

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This GCDH antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    序列

    IARQARDMLG GNGISDEYHV IRHAMNLEAV NTYEGTHDIH ALILGRAITG

    预测反应

    Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against GCDH. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human GCDH
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 438 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

    Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • 抗原

    GCDH (Glutaryl-CoA Dehydrogenase (GCDH))

    别名

    GCDH

    背景

    GCDH belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits.The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
    Alias Symbols: ACAD5, GCD
    Protein Interaction Partner: UBC, FBXO6, ADRB2, RNF32, EXOC6, ECSIT, MAST1, CDC37, PSEN2, PSEN1, NOS3, APOE, A2M, UBD, MYC, GCDH,
    Protein Size: 438

    分子量

    48 kDa

    基因ID

    2639

    NCBI登录号

    NM_000159, NP_000150

    UniProt

    Q92947
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