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STEAP3 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects STEAP3 in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 兔 和 Pig.
产品编号 ABIN2781309
发货至: 中国
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Quick Overview for STEAP3 抗体 (N-Term) (ABIN2781309)

抗原

See all STEAP3 抗体
STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

适用

  • 39
  • 19
  • 18
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 兔, Pig

宿主

  • 39
兔

克隆类型

  • 39
多克隆

标记

  • 23
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This STEAP3 antibody is un-conjugated

应用范围

  • 27
  • 18
  • 10
  • 10
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    STEAP3 Antibody - N-terminal region

    序列

    LVGSGFKVVV GSRNPKRTAR LFPSAAQVTF QEEAVSSPEV IFVAVFREHY

    预测反应

    Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 93%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against STEAP3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human STEAP3
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8112922

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

    别名

    STEAP3

    背景

    Background Information: AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+) and can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD(+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT

    Gene Name: STEAP family member 3, metalloreductase

    Alternative Symbols: STMP3, TSAP6, pH yde, AHMIO2, dudlin-2, dudulin-2

    Protein Name: Metalloreductase STEAP3

    分子量

    54kDa

    基因ID

    55240

    NCBI登录号

    NP_001008410

    UniProt

    Q658P3

    途径

    Transition Metal Ion Homeostasis
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