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STEAP3 抗体 (C-Term)

This anti-STEAP3 antibody is a 兔 多克隆 antibody detecting STEAP3 in WB. Suitable for 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马 和 兔.
产品编号 ABIN2781298
发货至: 中国
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Quick Overview for STEAP3 抗体 (C-Term) (ABIN2781298)

抗原

See all STEAP3 抗体
STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

适用

  • 36
  • 15
  • 15
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 兔

宿主

  • 36

克隆类型

  • 36
多克隆

标记

  • 20
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This STEAP3 antibody is un-conjugated

应用范围

  • 24
  • 17
  • 8
  • 7
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    VALVLSTLHT LTYGWTRAFE ESRYKFYLPP TFTLTLLVPC VVILAKALFL

    预测反应

    Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against STEAP3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human STEAP3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 498 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

    别名

    STEAP3

    背景

    AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+) and can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD(+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT.
    Alias Symbols: STMP3, TSAP6, dudlin-2
    Protein Interaction Partner: UBC, SETD7, BAD, TPT1, BNIP3L, PKMYT1,
    Protein Size: 498

    分子量

    56 kDa

    基因ID

    55240

    NCBI登录号

    NM_182915, NP_878919

    UniProt

    A8K6E3

    途径

    Transition Metal Ion Homeostasis
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