FOXM1 抗体 (Forkhead Box M1) (Middle Region)

Details for Product anti-FOXM1 Antibody No. ABIN2781166, 供应商: Log in to see
抗原
  • FKHL16
  • FOXM1B
  • HFH-11
  • HFH11
  • HNF-3
  • INS-1
  • MPHOSPH2
  • MPP-2
  • MPP2
  • PIG29
  • TGT3
  • TRIDENT
  • FOXM1
  • AA408308
  • AW554517
  • BB238854
  • Fkh16
  • Foxm1b
  • HFH-11B
  • Mpm2
  • WIN
  • Trident
  • fkhl16
  • foxm1l
  • hfh-11
  • mpp2
  • zgc:63854
  • forkhead box M1
  • forkhead box M1 S homeolog
  • FOXM1
  • Foxm1
  • foxm1
  • foxm1.S
抗原表位
Middle Region
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8
6
5
4
4
4
3
3
3
3
2
2
2
1
1
1
1
1
1
1
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适用
犬, 豚鼠, 人, 小鼠, 兔, 大鼠
96
39
39
5
3
2
2
2
宿主

78
20
克隆类型
多克隆
标记
This FOXM1 antibody is un-conjugated
2
2
2
1
1
1
1
1
1
1
1
1
1
1
应用范围
Western Blotting (WB)
74
34
22
13
11
11
10
9
4
4
3
1
1
1
选项
Supplier
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Supplier Product No.
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免疫原 The immunogen is a synthetic peptide directed towards the middle region of human FOXM1
Blocking Peptide Blocking peptide for this product available: ABIN977056
序列 ANRSLTEGLV LDTMNDSLSK ILLDISFPGL DEDPLGPDNI NWSQFIPELQ
预测反应 Dog: 79%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
产品特性 This is a rabbit polyclonal antibody against FOXM1. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
Plasmids, Primers & others Plasmids, Primers & others FOXM1 products on genomics-online (e.g. as negative or positive controls)
抗原
别名 FOXM1 (FOXM1 Antibody 摘要)
背景 This protein acts as a Transcriptional activatory factor. May play a role in the control of cell proliferation.
Alias Symbols: FKHL16, FOXM1B, HFH-11, HFH11, HNF-3, INS-1, MPHOSPH2, MPP-2, MPP2, PIG29, TGT3, TRIDENT
Protein Interaction Partner: SMAD3, FZR1, SUMO1, UBE2I, SP1, CDK2, CCNE1, BANP, OS9, HSP90AA1, CDK6, CDK4, DHX29, ACAT1, CDC27, UBC, BCL6, SUMO2, RB1, CREBBP, CDC25B, CDK1, CCNB1, ZBTB3, CHEK2, STAT3, CDH1, CENPF,
Protein Size: 763
分子量 84 kDa
基因ID 2305
NCBI登录号 NM_021953, NP_068772
UniProt Q08050
途径 Positive Regulation of Response to DNA Damage Stimulus
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 763 AA

限制 仅限研究用
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
厂商提供的图像
Western Blotting (WB) image for anti-Forkhead Box M1 (FOXM1) (Middle Region) antibody (ABIN2781166) WB Suggested Anti-FOXM1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Posi...
Western Blotting (WB) image for anti-Forkhead Box M1 (FOXM1) (Middle Region) antibody (ABIN2781166) Lanes: Lane 1: 25ug MIA PaCa-2 human pancreatic cancer cell line) Lane 2: 25ug MD...
有引用在: Hu, Liu, Zhang, Lou, Huang, Chen, Shen, Gao, Gong, Zhou, Dai, Zeng, He: "LXR?-mediated downregulation of FOXM1 suppresses the proliferation of hepatocellular carcinoma cells." in: Oncogene, Vol. 33, Issue 22, pp. 2888-97, 2014 (PubMed).

背景 Laoukili, Alvarez, Meijer, Stahl, Mohammed, Kleij, Heck, Medema: "Activation of FoxM1 during G2 requires cyclin A/Cdk-dependent relief of autorepression by the FoxM1 N-terminal domain." in: Molecular and cellular biology, Vol. 28, Issue 9, pp. 3076-87, 2008 (PubMed).