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PRDM12 抗体 (C-Term)

This 兔 多克隆 anti-PRDM12 antibody specifically detects PRDM12 in WB. The antibody is reactive with 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼 和 Pig samples.
产品编号 ABIN2781154
发货至: 中国
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Quick Overview for PRDM12 抗体 (C-Term) (ABIN2781154)

抗原

See all PRDM12 抗体
PRDM12 (PR Domain Containing 12 (PRDM12))

适用

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人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, Pig

宿主

  • 20
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克隆类型

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多克隆

标记

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This PRDM12 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    NHVRLHTGER PYKCQVCQSA YSQLAGLRAH QKSARHRPPS TALQAHSPAL

    预测反应

    Cow: 93%, Dog: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against PRDM12. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human PRDM12
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 367 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PRDM12 (PR Domain Containing 12 (PRDM12))

    别名

    PRDM12

    背景

    PRDM12 belongs to PR-domain family which are involved in human cancers in an unusual yin-yang fashion. Two products are normally produced from a PR-domain family member which differ by the presence or absence of the PR domain, the PR-plus product is disrupted or underexpressed whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, a result of either genetic or epigenetic events, appears to be an important cause of malignancy. PRDM12 may have a potential role in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion.
    Alias Symbols: PFM9
    Protein Size: 367

    分子量

    40 kDa

    基因ID

    59335

    NCBI登录号

    NM_021619, NP_067632

    UniProt

    Q9H4Q4
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