PRDM12 抗体 (C-Term)
Quick Overview for PRDM12 抗体 (C-Term) (ABIN2781154)
抗原
See all PRDM12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- NHVRLHTGER PYKCQVCQSA YSQLAGLRAH QKSARHRPPS TALQAHSPAL
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预测反应
- Cow: 93%, Dog: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against PRDM12. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PRDM12
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 367 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PRDM12 (PR Domain Containing 12 (PRDM12))
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别名
- PRDM12
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背景
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PRDM12 belongs to PR-domain family which are involved in human cancers in an unusual yin-yang fashion. Two products are normally produced from a PR-domain family member which differ by the presence or absence of the PR domain, the PR-plus product is disrupted or underexpressed whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, a result of either genetic or epigenetic events, appears to be an important cause of malignancy. PRDM12 may have a potential role in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion.
Alias Symbols: PFM9
Protein Size: 367 -
分子量
- 40 kDa
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基因ID
- 59335
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NCBI登录号
- NM_021619, NP_067632
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UniProt
- Q9H4Q4
抗原
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