KDM6A 抗体 (Middle Region)
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北京 101111
Quick Overview for KDM6A 抗体 (Middle Region) (ABIN2781142)
抗原
See all KDM6A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- KTYIVHCQDC ARKTSGNLEN FVVLEQYKME DLMQVYDQFT LAPPLPSASS
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against UTX. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human UTX
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anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (AA 641-740) antibody
KDM6A 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4E7 unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (AA 1252-1401) antibodyKDM6A 适用: 人, 大鼠 WB, ELISA 宿主: 小鼠 Monoclonal 6E2D6 unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (AA 1252-1401) antibodyKDM6A 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5C2A9 unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (C-Term) antibodyKDM6A 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 豚鼠, 马, 兔, Pig, 小鸡, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (AA 620-749) antibodyKDM6A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (AA 1041-1074), (C-Term) antibodyKDM6A 适用: 小鼠 WB 宿主: 兔 Polyclonal RB52352 unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (AA 797-832) antibodyKDM6A 适用: 人 WB 宿主: 兔 Polyclonal RB51279 unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (AA 245-294) antibodyKDM6A 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 豚鼠, 马, Pig, 小鸡, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) antibodyKDM6A 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6A (KDM6A) (N-Term) antibodyKDM6A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1401 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))
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别名
- UTX
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背景
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UTX is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitent with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
Alias Symbols: DKFZp686A03225, MGC141941, bA386N14.2, UTX, KABUK2
Protein Interaction Partner: KMT2D, WDR5, ASH2L, RBBP5, SMAD9, HIST2H3C, SRF, SMARCA4, GATA4, NKX2-5, TBX5, UBC, HIST1H3A, WDR82, PAXIP1, NCOA6, TLE1, PROSER1, KMT2C, N4BP2, PPP6R3, ZNF281, HIST3H3,
Protein Size: 1401 -
分子量
- 154 kDa
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基因ID
- 7403
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NCBI登录号
- NM_021140, NP_066963
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UniProt
- O15550
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途径
- Tube Formation, Warburg Effect
抗原
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