KDM6A 抗体 (C-Term)
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北京 101111
Quick Overview for KDM6A 抗体 (C-Term) (ABIN2781142)
抗原
See all KDM6A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- UTX Antibody - C-terminal region
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序列
- KTYIVHCQDC ARKTSGNLEN FVVLEQYKME DLMQVYDQFT LAPPLPSASS
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against UTX. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of human UTX
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39483-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))
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别名
- UTX
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背景
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Background Information: UTX is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitent with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
Gene Name: Lysine (K)-specific demethylase 6A
Alternative Symbols: UTX, KABUK2, bA386N14.2
Protein Name: Lysine-specific demethylase 6A
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分子量
- 154kDa
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基因ID
- 7403
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NCBI登录号
- NP_066963
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UniProt
- O15550
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途径
- Tube Formation, Warburg Effect
抗原
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