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AHRR 抗体 (Middle Region)

This anti-AHRR antibody is a 兔 多克隆 antibody detecting AHRR in WB. Suitable for 人, 小鼠, 大鼠, 犬, 马, Cow 和 豚鼠.
产品编号 ABIN2781113
发货至: 中国

Quick Overview for AHRR 抗体 (Middle Region) (ABIN2781113)

抗原

See all AHRR 抗体
AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

适用

人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠

宿主

  • 22
  • 4

克隆类型

  • 23
  • 3
多克隆

标记

  • 15
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This AHRR antibody is un-conjugated

应用范围

  • 14
  • 12
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    LPQSEPPHQL CARGRGEQSC TCRAAEAAPV VKREPLDSPQ WATHSQGMVP

    预测反应

    Cow: 82%, Dog: 85%, Guinea Pig: 91%, Horse: 79%, Human: 100%, Mouse: 91%, Rat: 91%

    产品特性

    This is a rabbit polyclonal antibody against AHRR. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human AHRR
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 719 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

    别名

    AHRR

    背景

    Dioxin is a teratogen that exerts its effects through the arylhydrocarbon receptor in conjunction with the receptor's binding partner, arylhydrocarbon receptor nuclear translocator. AHRR represses signal transduction by the arylhydrocarbon receptor by competing with the arylhydrocarbon receptor nuclear translocator for binding to the arylhydrocarbon receptor. Expression of the repressor is stimulated by the receptor/translocator heterodimer, thereby regulating receptor function through a negative feedback mechanism. In addition, AHRR can bind to nuclear factor kappa-B.Dioxin is a teratogen that exerts its effects through the arylhydrocarbon receptor in conjunction with the receptor's binding partner, arylhydrocarbon receptor nuclear translocator. The protein encoded by this gene represses signal transduction by the arylhydrocarbon receptor by competing with the arylhydrocarbon receptor nuclear translocator for binding to the arylhydrocarbon receptor. Expression of the repressor is stimulated by the receptor/translocator heterodimer, thereby regulating receptor function through a negative feedback mechanism. In addition, the encoded protein can bind to nuclear factor kappa-B. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: AHH, AHHR, KIAA1234, MGC167813, MGC176630, bHLHe77
    Protein Interaction Partner: ANKRA2, HDAC5, HDAC4, ESR1, ARNT,
    Protein Size: 719

    分子量

    78 kDa

    基因ID

    57491

    NCBI登录号

    NM_020731, NP_065782

    UniProt

    A9YTQ3

    途径

    Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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