MNT 抗体 (N-Term)
Quick Overview for MNT 抗体 (N-Term) (ABIN2781100)
抗原
See all MNT 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- N-Term
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                                            序列
- SIETLLEAAR FLEWQAQQQQ RAREEQERLR LEQEREQEQK KANSLARLAH
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                                            预测反应
- Cow: 93%, Dog: 93%, Horse: 80%, Human: 100%, Mouse: 93%, Pig: 80%, Rabbit: 93%, Rat: 93%, Yeast: 92%
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                                            产品特性
- This is a rabbit polyclonal antibody against MNT. It was validated on Western Blot using a cell lysate as a positive control.
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                                            纯化方法
- Affinity Purified
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                                            免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MNT
 
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                                            应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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                                            说明
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                        Antigen size: 582 AA 
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- Lot specific
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                                            缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- Avoid repeated freeze-thaw cycles.
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                                            储存条件
- -20 °C
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                                            储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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    - MNT (MNT, MAX Dimerization Protein (MNT))
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                                            别名
- MNT
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                                            背景
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                        The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. MNT is a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
 Alias Symbols: MAD6, MXD6, ROX, bHLHd3
 Protein Interaction Partner: Dlg4, ELAVL1, CEBPA, MAX, MAD1L1, MYC, HDAC1, SIN3A, MNT, MLX, HMGB1,
 Protein Size: 582
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                                            分子量
- 62 kDa
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                                            基因ID
- 4335
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                                            NCBI登录号
- NM_020310, NP_064706
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                                            UniProt
- Q99583
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                                            途径
- Chromatin Binding, Regulation of Muscle Cell Differentiation
 抗原
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