DMAP1 抗体 (N-Term)
Quick Overview for DMAP1 抗体 (N-Term) (ABIN2781079)
抗原
See all DMAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MATGADVRDI LELGGPEGDA ASGTISKKDI INPDKKKSKK SSETLTFKRP
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against DMAP1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DMAP1
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anti-DNA Methyltransferase 1-Associated Protein 1 (DMAP1) (AA 1-305) antibody
DMAP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-DNA Methyltransferase 1-Associated Protein 1 (DMAP1) (AA 1-100) antibodyDMAP1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2G12 unconjugated
anti-DNA Methyltransferase 1-Associated Protein 1 (DMAP1) (AA 250-300) antibodyDMAP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA Methyltransferase 1-Associated Protein 1 (DMAP1) (AA 1-467) antibodyDMAP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-DNA Methyltransferase 1-Associated Protein 1 (DMAP1) (C-Term) antibodyDMAP1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-DNA Methyltransferase 1-Associated Protein 1 (DMAP1) antibodyDMAP1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-DNA Methyltransferase 1-Associated Protein 1 (DMAP1) (C-Term) antibodyDMAP1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, Bat, Hamster, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-DNA Methyltransferase 1-Associated Protein 1 (DMAP1) (N-Term) antibodyDMAP1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-DNA Methyltransferase 1-Associated Protein 1 (DMAP1) (AA 150-199) antibodyDMAP1 适用: 人, 小鼠, 犬, Cow, 豚鼠, 兔, 斑马鱼, 马, Bat, Hamster, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-DNA Methyltransferase 1-Associated Protein 1 (DMAP1) antibodyDMAP1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 467 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))
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别名
- DMAP1
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背景
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DMAP1 is a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.
Alias Symbols: EAF2, SWC4, MEAF2, DNMAP1, DNMTAP1
Protein Interaction Partner: SOX2, UBC, RNF2, HECW2, RUVBL2, SRCAP, CFDP1, RUVBL1, DENR, VPS72, TOMM34, TSG101, H2AFZ, DAXX, SMARCAD1, SUMO2, EPC1, ACTL6A, ACTA1, PPP2R2D, ING3, MORF4L1, BRD8, KAT5, TRRAP, YEATS4, EP400, EPC2, MYC, MAX, ACTG1, ACTB, MRGBP, MORF4L2, MNAT1, HDAC1, tat,
Protein Size: 467 -
分子量
- 53 kDa
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基因ID
- 55929
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NCBI登录号
- NM_019100, NP_061973
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UniProt
- Q9NPF5
抗原
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