我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

BCL11A 抗体 (N-Term)

Name: BCL11A 抗体 (N-Term)
SKU: ABIN2781048
Availability: OutOfStock

This anti-BCL11A antibody is a 兔多克隆 antibody detecting BCL11A in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 马, Pig 和斑马鱼. This Primary Antibody has been cited in 1 publication.

WB Suggested Anti-BCL11A Antibody Titration: 0. (BCL11A 抗体 (N-Term))

Immunohistochemistry with Human Spleen lysate tissue at an antibody concentration of 5. (BCL11A 抗体 (N-Term))

IHC

2 images

(1 reference)

产品编号 ABIN2781048

发货至: 中国

Quick Overview for BCL11A 抗体 (N-Term) (ABIN2781048)

抗原

See all BCL11A 抗体

BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

适用

人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 斑马鱼

宿主

兔

克隆类型

多克隆

标记

This BCL11A antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product BCL11A Primary Antibody

抗原表位
15

12

10

4

3

3

3

2

2

2

2

2

1

1
N-Term

序列

MSRRKQGKPQ HLSKREFSPE PLEAILTDDE PDHGPLGAPE GDHDLLTCGQ

预测反应

Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%

产品特性

This is a rabbit polyclonal antibody against BCL11A. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human BCL11A
anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (AA 1-88) antibody
BCL11A 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3D9 unconjugated

anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (N-Term) antibody
BCL11A 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 斑马鱼, 小鸡, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (AA 1-230) antibody
BCL11A 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (AA 1-89) antibody
BCL11A 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D9 unconjugated

anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (AA 1-243) antibody
BCL11A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) antibody
BCL11A 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (AA 1-210) antibody
BCL11A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (AA 1-88) antibody
BCL11A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (AA 1-243) antibody
BCL11A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (AA 637-835) antibody
BCL11A 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal BCL11A-123 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 835 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Uda, Galanello, Sanna, Lettre, Sankaran, Chen, Usala, Busonero, Maschio, Albai, Piras, Sestu, Lai, Dei, Mulas, Crisponi, Naitza, Asunis, Deiana, Nagaraja, Perseu, Satta, Cipollina, Sollaino, Moi, Hirschhorn, Orkin, Abecasis, Schlessinger, Cao: "Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 5, pp. 1620-5, (2008) (PubMed).
抗原

BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

别名

BCL11A

背景

BCL11A Is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression.This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.
Alias Symbols: BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, ZNF856
Protein Interaction Partner: GMCL1P1, ZBTB24, NCK2, LMO1, NR2E3, NR2E1, NR2F2, NR2F1, NR2F6, HDAC2, HDAC1, CDCA3, YME1L1, CDK6, CDK4, ACTC1, APP, UBC, BCL6, BCL11A, Sumo1, SUMO2, SUMO3, SIRT1, MBD3, MTA2, MTA1, CHD4,
Protein Size: 835

分子量

91 kDa

基因ID

53335

NCBI登录号

NM_022893, NP_075044

UniProt

Q9H165

途径

Regulation of Cell Size