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SART3 抗体 (N-Term)

This anti-SART3 antibody is a 兔 多克隆 antibody detecting SART3 in WB 和 IHC. Suitable for 人, 大鼠, 豚鼠, 犬, 马 和 Pig. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2780944
发货至: 中国

Quick Overview for SART3 抗体 (N-Term) (ABIN2780944)

抗原

See all SART3 抗体
SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))

适用

  • 30
  • 6
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  • 2
  • 2
  • 2
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  • 1
  • 1
人, 大鼠, 豚鼠, 犬, 马, Pig

宿主

  • 27
  • 2
  • 1

克隆类型

  • 30
多克隆

标记

  • 20
  • 2
  • 1
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This SART3 antibody is un-conjugated

应用范围

  • 18
  • 10
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  • 3
  • 2
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 5
    • 4
    • 3
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    • 1
    • 1
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    N-Term

    序列

    TSASEPEAES KAGPKADGEE DEVKAARTRR KVLSRAVAAA TYKTMGPAWD

    预测反应

    Dog: 77%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Pig: 86%, Rat: 79%

    产品特性

    This is a rabbit polyclonal antibody against SART3. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human SART3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 364 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Kaji, Mizukoshi, Yamashita, Arai, Sunagozaka, Fushimi, Nakagawa, Yamada, Terashima, Kitahara, Kaneko: "Cellular Immune Responses for Squamous Cell Carcinoma Antigen Recognized by T Cells 3 in Patients with Hepatocellular Carcinoma." in: PLoS ONE, Vol. 12, Issue 1, pp. e0170291, (2017) (PubMed).

  • 抗原

    SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))

    别名

    SART3

    背景

    SART3 is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. SART3 is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This protein is thought to be involved in the regulation of mRNA splicing.
    Alias Symbols: P100, p110, DSAP1, TIP110, p110(nrb), RP11-13G14
    Protein Interaction Partner: APBB1, PRPF3, Usp15, AMOT, SF3B1, NUP160, LRPPRC, THRAP3, BCLAF1, VARS, UBC, SUMO2, RAB1A, NEFM, IARS, HIF1A, DSG2, DHX9, MEPCE, HIST2H2BE, HIST2H2AC, RNF2, BMI1, RUFY1, NRBP1, PSME4, AKAP2, COPS5, NUP50, POP7, ARHGEF10, PSMB3, PSMA5, PSMA3, POLR2H, CAST,
    Protein Size: 364

    分子量

    40 kDa

    基因ID

    9733

    NCBI登录号

    NM_014706

    途径

    Ribonucleoprotein Complex Subunit Organization
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