PATZ1 抗体 (Middle Region)
Quick Overview for PATZ1 抗体 (Middle Region) (ABIN2780923)
抗原
See all PATZ1 (ZNF278) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- SFFRSKSYLN KHIQKVHVRA LGGPLGDLGP ALGSPFSPQQ NMSLLESFGF
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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产品特性
- This is a rabbit polyclonal antibody against PATZ1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PATZ1
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anti-Zinc Finger Protein 278 (ZNF278) (AA 260-358) antibody
ZNF278 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B2 unconjugated
anti-Zinc Finger Protein 278 (ZNF278) (N-Term) antibodyZNF278 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 278 (ZNF278) (N-Term) antibodyZNF278 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 278 (ZNF278) (AA 351-450) antibodyZNF278 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 278 (ZNF278) (AA 1-537) antibodyZNF278 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger Protein 278 (ZNF278) antibodyZNF278 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 278 (ZNF278) (AA 612-661) antibodyZNF278 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, Bat, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 278 (ZNF278) (N-Term) antibodyZNF278 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 278 (ZNF278) (AA 35-84) antibodyZNF278 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 278 (ZNF278) (AA 250-350) antibodyZNF278 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 687 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))
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别名
- PATZ1
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背景
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PATZ1 contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1,22)(p36.1,q12).The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1,22)(p36.1,q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene.
Alias Symbols: MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG, dJ400N23
Protein Interaction Partner: TP53, SOX2, PRKAR1A, BCL6, BACH2, RNF4, BACH1, MITF, AR,
Protein Size: 687 -
分子量
- 74 kDa
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基因ID
- 23598
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NCBI登录号
- NM_014323, NP_055138
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UniProt
- Q9HBE1
抗原
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