CNOT7 抗体 (N-Term)
Quick Overview for CNOT7 抗体 (N-Term) (ABIN2780900)
抗原
See all CNOT7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- TEFPGVVARP IGEFRSNADY QYQLLRCNVD LLKIIQLGLT FMNEQGEYPP
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against CNOT7. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CNOT7
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 262 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Alterations of deadenylase expression in acute leukemias: evidence for poly(a)-specific ribonuclease as a potential biomarker." in: Acta haematologica, Vol. 128, Issue 1, pp. 39-46, (2012) (PubMed).
: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
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Alterations of deadenylase expression in acute leukemias: evidence for poly(a)-specific ribonuclease as a potential biomarker." in: Acta haematologica, Vol. 128, Issue 1, pp. 39-46, (2012) (PubMed).
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- CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))
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别名
- CNOT7
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背景
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CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs.The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
Alias Symbols: CAF1, hCAF-1
Protein Interaction Partner: FBXW11, TOB2, BTG2, FOXC2, UBC, BAG3, CNOT6, AGO2, AGO1, EPAS1, APP, ELAVL1, BTG1, Cnot3, HOXD4, IKBKG, BTG3, TOB1, CDK6, CDK4, CDK2, CDK1, PABPC1,
Protein Size: 262 -
分子量
- 30 kDa
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基因ID
- 29883
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NCBI登录号
- NM_013354, NP_037486
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UniProt
- Q9UIV1
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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