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CNOT7 抗体 (N-Term)

This anti-CNOT7 antibody is a 兔 多克隆 antibody detecting CNOT7 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, 兔, 豚鼠, 山羊 和 Saccharomyces cerevisiae. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN2780900
发货至: 中国

Quick Overview for CNOT7 抗体 (N-Term) (ABIN2780900)

抗原

See all CNOT7 抗体
CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

适用

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人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, 兔, 豚鼠, 山羊, Saccharomyces cerevisiae

宿主

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克隆类型

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多克隆

标记

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This CNOT7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    TEFPGVVARP IGEFRSNADY QYQLLRCNVD LLKIIQLGLT FMNEQGEYPP

    预测反应

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against CNOT7. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human CNOT7
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 262 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Maragozidis, Karangeli, Labrou, Dimoulou, Papaspyrou, Salataj, Pournaras, Matsouka, Gourgoulianis, Balatsos: "Alterations of deadenylase expression in acute leukemias: evidence for poly(a)-specific ribonuclease as a potential biomarker." in: Acta haematologica, Vol. 128, Issue 1, pp. 39-46, (2012) (PubMed).

    Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • 抗原

    CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

    别名

    CNOT7

    背景

    CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs.The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
    Alias Symbols: CAF1, hCAF-1
    Protein Interaction Partner: FBXW11, TOB2, BTG2, FOXC2, UBC, BAG3, CNOT6, AGO2, AGO1, EPAS1, APP, ELAVL1, BTG1, Cnot3, HOXD4, IKBKG, BTG3, TOB1, CDK6, CDK4, CDK2, CDK1, PABPC1,
    Protein Size: 262

    分子量

    30 kDa

    基因ID

    29883

    NCBI登录号

    NM_013354, NP_037486

    UniProt

    Q9UIV1

    途径

    Ribonucleoprotein Complex Subunit Organization
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