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HBP1 抗体 (Middle Region)

HBP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780873
发货至: 中国
  • 抗原 See all HBP1 抗体
    HBP1 (HMG Box-Containing Protein 1 (HBP1))
    抗原表位
    • 15
    • 12
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 44
    • 41
    • 17
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, 斑马鱼
    宿主
    • 58
    • 1
    克隆类型
    • 59
    多克隆
    标记
    • 24
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HBP1 antibody is un-conjugated
    应用范围
    • 37
    • 18
    • 13
    • 13
    • 8
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    SVILGDRWKK MKNEERRMYT LEAKALAEEQ KRLNPDCWKR KRTNSGSQQH
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
    产品特性
    This is a rabbit polyclonal antibody against HBP1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human HBP1
    Top Product
    Discover our top product HBP1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 514 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Wang, Pan, Chen, Huang, Zhang: "The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression." in: Nucleic acids research, Vol. 40, Issue 3, pp. 981-95, (2012) (PubMed).

    Li, Bian, Liao, Li, Zhao: "miR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1." in: Breast cancer research and treatment, Vol. 126, Issue 3, pp. 565-75, (2011) (PubMed).

  • 抗原
    HBP1 (HMG Box-Containing Protein 1 (HBP1))
    别名
    HBP1 (HBP1 产品)
    别名
    1700058O05Rik antibody, BE629963 antibody, C330012F01Rik antibody, C86454 antibody, hbp1-B antibody, Hmgb1 antibody, wu:fj62c10 antibody, zgc:112297 antibody, high mobility group box transcription factor 1 antibody, HMG-box transcription factor 1 antibody, HMG-box transcription factor 1 L homeolog antibody, Hbp1 antibody, HBP1 antibody, hbp1.L antibody, hbp1 antibody
    背景
    HBP1 is a transcriptional repressor that binds to the promoter region of target genes. This protein plays a role in the regulation of the cell cycle and of the Wnt pathway. It binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter, HBP1 is enhanced by interaction with RB1. The protein also can disrupt the interaction between DNA and TCF4.
    Alias Symbols: FLJ16340
    Protein Interaction Partner: FBXW11, UBC, TMEM37, SMAD1, ZNF212, KIAA1279, EWSR1, CD2AP, EP300, CREBBP, MYC, ANKRD2, SIN3A, SAP30, TCF4, HDAC1, RBL2, RB1,
    Protein Size: 514
    分子量
    58 kDa
    基因ID
    26959
    NCBI登录号
    NM_012257, NP_036389
    UniProt
    O60381
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