HBP1 抗体 (Middle Region)
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北京 101111
Quick Overview for HBP1 抗体 (Middle Region) (ABIN2780873)
抗原
See all HBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- SVILGDRWKK MKNEERRMYT LEAKALAEEQ KRLNPDCWKR KRTNSGSQQH
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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产品特性
- This is a rabbit polyclonal antibody against HBP1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human HBP1
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anti-HMG Box-Containing Protein 1 (HBP1) (AA 421-514) antibody
HBP1 适用: 小鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (pSer402) antibodyHBP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (C-Term) antibodyHBP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (pSer402) antibodyHBP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (C-Term) antibodyHBP1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (AA 1-514) antibodyHBP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (C-Term) antibodyHBP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴, 豚鼠, 小鸡, 马, 兔, 非洲爪蟾, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (AA 396-445) antibodyHBP1 适用: 人, 大鼠, 犬, 猴, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (Middle Region) antibodyHBP1 适用: 人, 小鼠, 大鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-HMG Box-Containing Protein 1 (HBP1) (Middle Region) antibodyHBP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 小鸡, 斑马鱼, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 514 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression." in: Nucleic acids research, Vol. 40, Issue 3, pp. 981-95, (2012) (PubMed).
: "miR-17-5p promotes human breast cancer cell migration and invasion through suppression of HBP1." in: Breast cancer research and treatment, Vol. 126, Issue 3, pp. 565-75, (2011) (PubMed).
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: "The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression." in: Nucleic acids research, Vol. 40, Issue 3, pp. 981-95, (2012) (PubMed).
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- HBP1 (HMG Box-Containing Protein 1 (HBP1))
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别名
- HBP1
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背景
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HBP1 is a transcriptional repressor that binds to the promoter region of target genes. This protein plays a role in the regulation of the cell cycle and of the Wnt pathway. It binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter, HBP1 is enhanced by interaction with RB1. The protein also can disrupt the interaction between DNA and TCF4.
Alias Symbols: FLJ16340
Protein Interaction Partner: FBXW11, UBC, TMEM37, SMAD1, ZNF212, KIAA1279, EWSR1, CD2AP, EP300, CREBBP, MYC, ANKRD2, SIN3A, SAP30, TCF4, HDAC1, RBL2, RB1,
Protein Size: 514 -
分子量
- 58 kDa
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基因ID
- 26959
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NCBI登录号
- NM_012257, NP_036389
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UniProt
- O60381
抗原
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