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TRIM32 抗体 (N-Term)

Cited in 2+ publications. The 兔多克隆 anti-TRIM32 antibody (ABIN2780865) specifically detects TRIM32 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 犬, Cow, 马, 兔和豚鼠 samples.

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(2 references)

产品编号 ABIN2780865

发货至: 中国

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Quick Overview for TRIM32 抗体 (N-Term) (ABIN2780865)

抗原

See all TRIM32 抗体

TRIM32 (Tripartite Motif Containing 32 (TRIM32))

适用

人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This TRIM32 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product TRIM32 Primary Antibody

抗原表位
16

13

3

2

2

2

1

1

1

1

1

1

1
N-Term

原理

TRIM32 Antibody - N-terminal region

序列

MAAAAASHLN LDALREVLEC PICMESFTEE QLRPKLLHCG HTICRQCLEK

预测反应

Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 93%, Mouse: 93%, Rabbit: 93%, Rat: 93%

产品特性

This is a rabbit polyclonal antibody against TRIM32. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM32
anti-Tripartite Motif Containing 32 (TRIM32) (AA 105-204) antibody
TRIM32 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 2E5 unconjugated

anti-Tripartite Motif Containing 32 (TRIM32) antibody
TRIM32 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Tripartite Motif Containing 32 (TRIM32) (C-Term) antibody
TRIM32 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Tripartite Motif Containing 32 (TRIM32) (AA 559-608) antibody
TRIM32 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼, Pig, 小鸡, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Tripartite Motif Containing 32 (TRIM32) (AA 549-598) antibody
TRIM32 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼, Pig, 小鸡, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Tripartite Motif Containing 32 (TRIM32) (AA 1-280) antibody
TRIM32 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Tripartite Motif Containing 32 (TRIM32) (AA 105-204) antibody
TRIM32 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated

anti-Tripartite Motif Containing 32 (TRIM32) (AA 301-400) antibody
TRIM32 适用: 小鼠 WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Tripartite Motif Containing 32 (TRIM32) (C-Term) antibody
TRIM32 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Tripartite Motif Containing 32 (TRIM32) (N-Term) antibody
TRIM32 适用: 人, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

说明

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38965-100UG

限制

仅限研究用
状态

Liquid

浓度

1.0 mg/mL

缓冲液

Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

prevent freeze-thaw cycles

储存条件

4 °C,-20 °C

储存方法

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Streich, Ronchi, Connick, Haas: "Tripartite motif ligases catalyze polyubiquitin chain formation through a cooperative allosteric mechanism." in: The Journal of biological chemistry, Vol. 288, Issue 12, pp. 8209-21, (2013) (PubMed).

Kudryashova, Wu, Havton, Spencer: "Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component." in: Human molecular genetics, Vol. 18, Issue 7, pp. 1353-67, (2009) (PubMed).
抗原

TRIM32 (Tripartite Motif Containing 32 (TRIM32))

别名

TRIM32

背景

Background Information: TRIM32 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM32 localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.
Gene Name: Tripartite motif containing 32
Alternative Symbols: HT2A, BBS11, TATIP, LGMD2H, LGMDR8
Protein Name: E3 ubiquitin-protein ligase TRIM32

分子量

72kDa

基因ID

22954

NCBI登录号

NP_036342

UniProt

Q13049

途径

Negative Regulation of intrinsic apoptotic Signaling