TRIM32 抗体 (N-Term)
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北京 101111
Quick Overview for TRIM32 抗体 (N-Term) (ABIN2780865)
抗原
See all TRIM32 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MAAAAASHLN LDALREVLEC PICMESFTEE QLRPKLLHCG HTICRQCLEK
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 93%, Mouse: 93%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against TRIM32. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM32
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anti-Tripartite Motif Containing 32 (TRIM32) (AA 105-204) antibody
TRIM32 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-Tripartite Motif Containing 32 (TRIM32) antibodyTRIM32 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 32 (TRIM32) (C-Term) antibodyTRIM32 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 32 (TRIM32) (AA 1-280) antibodyTRIM32 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 32 (TRIM32) (AA 105-204) antibodyTRIM32 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tripartite Motif Containing 32 (TRIM32) (AA 549-598) antibodyTRIM32 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼, Pig, 小鸡, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 32 (TRIM32) (AA 559-608) antibodyTRIM32 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼, Pig, 小鸡, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 32 (TRIM32) (C-Term) antibodyTRIM32 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 32 (TRIM32) (AA 301-400) antibodyTRIM32 适用: 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 32 (TRIM32) (AA 1-280) antibodyTRIM32 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 653 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Tripartite motif ligases catalyze polyubiquitin chain formation through a cooperative allosteric mechanism." in: The Journal of biological chemistry, Vol. 288, Issue 12, pp. 8209-21, (2013) (PubMed).
: "Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component." in: Human molecular genetics, Vol. 18, Issue 7, pp. 1353-67, (2009) (PubMed).
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: "Tripartite motif ligases catalyze polyubiquitin chain formation through a cooperative allosteric mechanism." in: The Journal of biological chemistry, Vol. 288, Issue 12, pp. 8209-21, (2013) (PubMed).
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- TRIM32 (Tripartite Motif Containing 32 (TRIM32))
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别名
- TRIM32
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背景
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TRIM32 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM32 localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.
Alias Symbols: HT2A, BBS11, TATIP, LGMD2H
Protein Interaction Partner: PTPN11, PDE9A, PTCD2, CLIP4, KCTD9, UBQLN1, TRIM32, RABAC1, ABI2, SCGB1A1, UBE2E1, UBE2D1, UBC, TP53, SDCBP, UBE2U, SYT6, MYCN, CEP250, CUL3, GPRASP2, GLIS2, YWHAB, TP73, UBE2D3, UBE2D2, HSP90AA1, SFN, YWHAQ, YWHAZ, YWHAH, YWHAG, YWHAE, NOTCH1, UBD, TOP1,
Protein Size: 653 -
分子量
- 72 kDa
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基因ID
- 22954
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NCBI登录号
- NM_012210, NP_036342
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UniProt
- Q13049
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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