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CREB3 抗体 (Middle Region)

This anti-CREB3 antibody is a 兔 多克隆 antibody detecting CREB3 in WB. Suitable for 人, Cow 和 犬. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2780771
发货至: 中国

Quick Overview for CREB3 抗体 (Middle Region) (ABIN2780771)

抗原

See all CREB3 抗体
CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

适用

  • 36
  • 5
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  • 4
  • 4
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  • 2
  • 2
  • 1
  • 1
人, Cow, 犬

宿主

  • 32
  • 3
  • 1

克隆类型

  • 33
  • 3
多克隆

标记

  • 24
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CREB3 antibody is un-conjugated

应用范围

  • 27
  • 14
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    PPLEWPFPDL FSEPLCRGPI LPLQANLTRK GGWLPTGSPS VILQDRYSG

    预测反应

    Cow: 80%, Dog: 80%, Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against CREB3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human CREB3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 371 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mamdani, Alda, Grof, Young, Rouleau, Turecki: "Lithium response and genetic variation in the CREB family of genes." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 4, pp. 500-4, (2008) (PubMed).

  • 抗原

    CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

    别名

    CREB3

    背景

    CREB3 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: LUMAN, LZIP, MGC15333, MGC19782
    Protein Interaction Partner: COPS5, HCFC1, JUN, CREB3L1, CREB3L3, CREB3, NFE2L3, NFE2L2, DDIT3, CEBPG, ATF4, ATF3, TTLL5, RRAS2, OS9, RABAC1, SQLE, BCAT2, CLP1, UBC, HDAC3, MALL, NFIL3, APPBP2, STX8, BNIP2, CCR1, EMD,
    Protein Size: 371

    分子量

    41 kDa

    基因ID

    10488

    NCBI登录号

    NM_006368, NP_006359

    UniProt

    O43889

    途径

    Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Maintenance of Protein Location, Unfolded Protein Response
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