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FOXO4 抗体 (C-Term)

This anti-FOXO4 antibody is a 兔 多克隆 antibody detecting FOXO4 in WB. Suitable for 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠 和 兔.
产品编号 ABIN2780728
发货至: 中国

Quick Overview for FOXO4 抗体 (C-Term) (ABIN2780728)

抗原

See all FOXO4 抗体
FOXO4 (Forkhead Box O4 (FOXO4))

适用

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人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔

宿主

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克隆类型

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多克隆

标记

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This FOXO4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    PPVMAGAPIP KVLGTPVLAS PTEDSSHDRM PQDLDLDMYM ENLECDMDNI

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against Foxo4. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 505 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    FOXO4 (Forkhead Box O4 (FOXO4))

    别名

    Foxo4

    背景

    Foxo4 is a transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. It down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. It represses smooth muscle cell differentiation by inhibiting the transcriptional coactivator activity of myocardin.
    Alias Symbols: Afxh, MGC117660, Mllt7, afx
    Protein Size: 505

    分子量

    54 kDa

    基因ID

    54601

    NCBI登录号

    NM_001005872, NP_001005872

    UniProt

    Q99MK2

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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