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SMAD1 抗体 (N-Term)

Name: SMAD1 抗体 (N-Term)
SKU: ABIN2780719
Availability: OutOfStock

This anti-SMAD1 antibody is a 兔多克隆 antibody detecting SMAD1 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, 豚鼠和兔.

SMAD1 antibody - N-terminal region validated by WB using Transfected 293T cell lysate at 2. (SMAD1 抗体 (N-Term))

Immunohistochemistry (IHC) image for anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (N-Term) antibody (ABIN2780719) (SMAD1 抗体 (N-Term))

IHC

Immunohistochemistry with Human Skin lysate tissue (SMAD1 抗体 (N-Term))

IHC

Host: Rabbit Target Name: SMAD9 Sample Tissue: Mouse Skeletal Muscle Antibody Dilution: 1ug/ml (SMAD1 抗体 (N-Term))

4 images

产品编号 ABIN2780719

发货至: 中国

Datasheet as PDF

Quick Overview for SMAD1 抗体 (N-Term) (ABIN2780719)

抗原

See all SMAD1 抗体

SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

适用

人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, 豚鼠, 兔

宿主

兔

克隆类型

多克隆

标记

This SMAD1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product SMAD1 Primary Antibody

抗原表位
24

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24

15

9

8

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1
N-Term

序列

MNVTSLFSFT SPAVKRLLGW KQGDEEEKWA EKAVDALVKK LKKKKGAMEE

特异性

This antibody reacts with SMAD1 + SMAD5 and to a lesser extent, SMAD8.

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

产品特性

This is a rabbit polyclonal antibody against SMAD1. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD1
anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-465) antibody
SMAD1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E9 unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-110) antibody
SMAD1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D3 unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-465) antibody
SMAD1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2A1 unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 202-335) antibody
SMAD1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (pSer187) antibody
SMAD1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 163-196) antibody
SMAD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (pSer465) antibody
SMAD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 20-330) antibody
SMAD1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 1356CT119-18-55 unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 163-196) antibody
SMAD1 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB43846 unconjugated

anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) (AA 1-465) antibody
SMAD1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A1 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 465 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

别名

SMAD1

背景

SMAD1 belongs to the SMAD family. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. SMAD1 mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, SMAD1 can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of SMAD1 forms a complex with SMAD4, which is important for its function in the transcription regulation. SMAD1 is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation.The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.
Alias Symbols: BSP1, JV4-1, JV41, MADH1, MADR1, BSP-1
Protein Interaction Partner: HDAC1, SMURF1, WDR77, AR, UBC, ACVRL1, SMAD4, LEMD3, MAPK1, GSK3B, ZNF521, ZNF423, AKR1B1, AP2A2, PIAS4, ZDHHC3, HBP1, IRF2BP1, SF3B1, MGA, ZNF510, ICK, GMEB1, ZEB2, PUM1, PIGQ, PIAS1, TTF2, KMT2D, ZNF76, XPC, TTF1, SOX5, SNRNP70, SMAD3, SMAD2, SMAD1, INP
Protein Size: 465

分子量

52 kDa

基因ID

4086

NCBI登录号

NM_005900, NP_005891

UniProt

Q99717

途径

Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development