SAP18 抗体 (N-Term)
Quick Overview for SAP18 抗体 (N-Term) (ABIN2780718)
抗原
See all SAP18 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- EIKKEPEKPI DREKTCPLLL RVFTTNNGRH HRMDEFSRGN VPSSELQIYT
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against SAP18. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SAP18
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anti-Sin3A-Associated Protein, 18kDa (SAP18) (AA 21-172) antibody
SAP18 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sin3A-Associated Protein, 18kDa (SAP18) (AA 30-79) antibodySAP18 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Bat, 小鸡, 猴, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sin3A-Associated Protein, 18kDa (SAP18) (AA 1-153) antibodySAP18 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B2 unconjugated
anti-Sin3A-Associated Protein, 18kDa (SAP18) (AA 1-153) antibodySAP18 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Sin3A-Associated Protein, 18kDa (SAP18) (AA 1-153) antibodySAP18 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Sin3A-Associated Protein, 18kDa (SAP18) (AA 2-153) antibodySAP18 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 153 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))
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别名
- SAP18
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背景
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Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP18 is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.
Alias Symbols: SAP18P, 2HOR0202
Protein Interaction Partner: INCA1, RBM39, UBC, RNF2, SUZ12, BMI1, CSNK2A2, MAGOH, EIF4A3, VCP, NFIA, SEPT2, MYO1C, IK, HNRNPU, HNRNPC, GTF3C1, SEPT7, CDC5L, U2AF1, SNRPD2, SMARCC2, SMARCB1, SRSF7, SRSF5, SRSF3, SRSF1, SAFB, S100A9, PSAP, NHP2L1, TPR, TFPI, SURF4, SSRP1, SSR3, LOC255
Protein Size: 153 -
分子量
- 18 kDa
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基因ID
- 10284
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NCBI登录号
- NM_005870, NP_005861
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UniProt
- O00422
抗原
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