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RBM5 抗体 (N-Term)

This anti-RBM5 antibody is a 兔 多克隆 antibody detecting RBM5 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 和 Saccharomyces cerevisiae.
产品编号 ABIN2780715
发货至: 中国

Quick Overview for RBM5 抗体 (N-Term) (ABIN2780715)

抗原

See all RBM5 抗体
RBM5 (RNA Binding Motif Protein 5 (RBM5))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Saccharomyces cerevisiae

宿主

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克隆类型

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多克隆

标记

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This RBM5 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    GSDKRVSRTE RSGRYGSIID RDDRDERESR SRRRDSDYKR SSDDRRGDRY

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 80%

    产品特性

    This is a rabbit polyclonal antibody against RBM5. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human RBM5
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 815 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    RBM5 (RNA Binding Motif Protein 5 (RBM5))

    别名

    RBM5

    背景

    RBM5 is a component of the spliceosome A complex.It regulates alternative splicing of a number of mRNAs. RBM5 may modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. RBM5 may both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, RBM5 promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
    Alias Symbols: FLJ39876, G15, H37, LUCA15, RMB5
    Protein Interaction Partner: UBC, RNF2, SUZ12, WDR77, WBP11, LSM8, PRPF19, U2SURP, SNRNP200, U2AF2, PRPF8, ILF3, DHX15, LIG4, COPS5, SF3A2, SUMO2, GAPDH, BCL2L1, LRIF1,
    Protein Size: 815

    分子量

    92 kDa

    基因ID

    10181

    NCBI登录号

    NM_005778, NP_005769

    UniProt

    P52756

    途径

    Ribonucleoprotein Complex Subunit Organization
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