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NFIL3 抗体 (N-Term)

The 兔 多克隆 anti-NFIL3 antibody is suitable to detect NFIL3 in samples from 人, Cow, 绵羊, 犬 和 Pig. It has been validated for WB 和 IHC.
产品编号 ABIN2780681
发货至: 中国
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Quick Overview for NFIL3 抗体 (N-Term) (ABIN2780681)

抗原

See all NFIL3 抗体
NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

适用

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人, Cow, 绵羊, 犬, Pig

宿主

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克隆类型

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多克隆

标记

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This NFIL3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    MQLRKMQTVK KEQASLDASS NVDKMMVLNS ALTEVSEDST TGEDVLLSEG

    预测反应

    Cow: 86%, Dog: 86%, Human: 100%, Pig: 79%, Sheep: 79%

    产品特性

    This is a rabbit polyclonal antibody against NFIL3. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human NFIL3
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 462 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

    别名

    NFIL3

    背景

    NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.
    Alias Symbols: E4BP4, IL3BP1, NFIL3A, NF-IL3A
    Protein Interaction Partner: AMOTL2, TRAF2, MAFF, BATF, NFIL3, MAFG, DDIT3, CBX8, SUMO2, UBC, CREB3, DR1,
    Protein Size: 462

    分子量

    51 kDa

    基因ID

    4783

    NCBI登录号

    NM_005384, NP_005375

    UniProt

    Q14211
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