MAF 抗体 (N-Term)
Quick Overview for MAF 抗体 (N-Term) (ABIN2780675)
抗原
See all MAF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MASELAMSNS DLPTSPLAME YVNDFDLMKF EVKKEPVETD RIISQCGRLI
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预测反应
- Cow: 100%, Dog: 82%, Guinea Pig: 79%, Horse: 82%, Human: 100%, Mouse: 100%, Pig: 82%, Rabbit: 82%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against MAF. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MAF
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 373 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
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别名
- MAF
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背景
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MAF acts as a transcriptional activator or repressor. It is involved in embryonic lens fiber cell development. It recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. MAF is also involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. When overexpressed, MAF represses anti-oxidant reponse element (ARE)-mediated transcription. It may be involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Alias Symbols: MGC71685, c-MAF
Protein Interaction Partner: MAFB, FOSL1, MAF, FOS, ATF4, AHR, SUMO1, UBE2I, PML, SIN3A, HDAC2, SMARCA5, CEBPA, KDM5B, MAFA, SOX9, EP300, MAFG, USF2, CREBBP, MYB, JUN, ETS1, HOXD12,
Protein Size: 373 -
分子量
- 38 kDa
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基因ID
- 4094
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NCBI登录号
- NM_001031804, NP_001026974
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UniProt
- O75444
抗原
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