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ETS2 抗体 (Middle Region)

This anti-ETS2 antibody is a 兔 多克隆 antibody detecting ETS2 in WB. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔, 绵羊, 山羊 和 斑马鱼.
产品编号 ABIN2780665
发货至: 中国

Quick Overview for ETS2 抗体 (Middle Region) (ABIN2780665)

抗原

See all ETS2 抗体
ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))

适用

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人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔, 绵羊, 山羊, 斑马鱼

宿主

  • 36
  • 6

克隆类型

  • 39
  • 3
多克隆

标记

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This ETS2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    DPDEVARRWG KRKNKPKMNY EKLSRGLRYY YDKNIIHKTS GKRYVYRFVC

    预测反应

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against ETS2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human ETS2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 469 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))

    别名

    ETS2

    背景

    ETS2 contains an ETS DNA-binding domain and belongs to the ETS family. ETS2 is a target of protein kinase C and upregulates GM-CSF. Ets2 and its targets play essential roles in endothelial cell function. Coexpression of Ets-2 and SRC-1 significantly associated with the rate of recurrence and HER expression in breast cancer. Overexpression of ETS2 is associated with human esophageal squamous cell carcinoma. ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ETS2IT1
    Protein Interaction Partner: UBC, RFWD2, TWIST1, POU5F1, TWIST2, ZFYVE9, SRA1, XPO1, TP53, SUMO2, EP300, CREBBP, NCOR1, NCOA3, SRC, ZMYND11, TDP2, STAT5B, CDK10, SMARCA4, JUN, ERG, ETS2, ETS1, NR3C1, GATA3, FOS, SPI1, BRCA1,
    Protein Size: 469

    分子量

    53 kDa

    基因ID

    2114

    NCBI登录号

    NM_005239, NP_005230

    UniProt

    P15036

    途径

    EGFR Signaling Pathway, Myometrial Relaxation and Contraction
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