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NRF1 抗体 (C-Term)

The 兔 多克隆 anti-NRF1 antibody is suitable to detect NRF1 in samples from 人 和 大鼠. It has been validated for WB 和 IHC.
产品编号 ABIN2780636
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for NRF1 抗体 (C-Term) (ABIN2780636)

抗原

See all NRF1 抗体
NRF1 (Nuclear Respiratory Factor 1 (NRF1))

适用

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人, 大鼠

宿主

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兔

克隆类型

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多克隆

标记

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This NRF1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    原理

    NRF1 Antibody - C-terminal region

    序列

    IVLSGETAAA VGALTGVQDA NGLFMADRAG RKWILTDKAT GLVQIPVSMY

    预测反应

    Human: 100%, Rat: 91%

    产品特性

    This is a rabbit polyclonal antibody against NRF1. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human NRF1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8106872

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    NRF1 (Nuclear Respiratory Factor 1 (NRF1))

    别名

    NRF1

    背景

    Background Information: NRF1 is a phosphorylated nuclear protein with a bZIP domain. This protein homodimerizes and functions as a transcription factor that activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth.This gene encodes a phosphorylated nuclear protein with a bZIP domain. This protein homodimerizes and functions as a transcription factor that activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized.

    Gene Name: Nuclear respiratory factor 1

    Alternative Symbols: ALPHA-PAL

    Protein Name: NRF1 protein EMBL AAH16925.1

    分子量

    56kDa

    基因ID

    4899

    NCBI登录号

    NP_005002

    UniProt

    Q96AN2

    途径

    Regulation of Lipid Metabolism by PPARalpha
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