HMGN1 抗体 (Middle Region)
(1 reference)-
- 抗原 See all HMGN1 抗体
- HMGN1 (High Mobility Group Nucleosome Binding Domain 1 (HMGN1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HMGN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QTKGKRGAKG KQAEVANQET KEDLPAENGE TKTEESPASD EAGEKEAKSD
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 93%, Rat: 79%
- 产品特性
- This is a rabbit polyclonal antibody against HMGN1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human HMGN1
- Top Product
- Discover our top product HMGN1 Primary Antibody
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anti-High Mobility Group Nucleosome Binding Domain 1 (HMGN1) antibody
HMGN1 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Nucleosome Binding Domain 1 (HMGN1) antibodyHMGN1 适用: 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Nucleosome Binding Domain 1 (HMGN1) (AA 1-96) antibodyHMGN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Nucleosome Binding Domain 1 (HMGN1) (AA 36-85) antibodyHMGN1 适用: 人, 小鼠, 大鼠, Cow, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Nucleosome Binding Domain 1 (HMGN1) (AA 1-100) antibodyHMGN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Nucleosome Binding Domain 1 (HMGN1) (C-Term) antibodyHMGN1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Nucleosome Binding Domain 1 (HMGN1) (C-Term) antibodyHMGN1 适用: 人, Cow, Pig, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Nucleosome Binding Domain 1 (HMGN1) (AA 19-28), (pSer20), (pSer24) antibodyHMGN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Nucleosome Binding Domain 1 (HMGN1) (Middle Region) antibodyHMGN1 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Nucleosome Binding Domain 1 (HMGN1) (AA 14-100) antibodyHMGN1 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 100 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation. ..." in: Nature genetics, Vol. 46, Issue 6, pp. 618-23, (2014) (PubMed).
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: "Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation. ..." in: Nature genetics, Vol. 46, Issue 6, pp. 618-23, (2014) (PubMed).
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- 抗原
- HMGN1 (High Mobility Group Nucleosome Binding Domain 1 (HMGN1))
- 别名
- HMGN1 (HMGN1 产品)
- 别名
- HMG14 antibody, hmg14 antibody, hmgn1 antibody, hmgn1b antibody, HMG-14 antibody, Hmg14 antibody, high mobility group nucleosome binding domain 1 antibody, high mobility group nucleosome binding domain 1 S homeolog antibody, high mobility group nucleosomal binding domain 1 antibody, non-histone chromosomal protein HMG-14 antibody, HMGN1 antibody, hmgn1.S antibody, hmgn1 antibody, Hmgn1 antibody, LOC785479 antibody
- 背景
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Chromosomal protein HMG14 (HMGN1) and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.Chromosomal protein HMG14 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ27265, FLJ31471, HMG14, MGC104230, MGC117425
Protein Interaction Partner: UBC, RPS6KA3, PRKCA, PRKACG, SLC38A3, PPP1CC, LIG4, PPIP5K1, TERF2, SPP1, POLR2A, ERCC8, HDGF, EP300, BTG2, ERCC6, NFE2, RPS6KA5, RPS6KA4, PRKACA, YWHAZ, HMGN1, HMGN2, IRF2,
Protein Size: 100 - 分子量
- 11 kDa
- 基因ID
- 3150
- NCBI登录号
- NM_004965, NP_004956
- UniProt
- Q6NSG7
- 途径
- Chromatin Binding
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