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ONECUT1 抗体 (Middle Region)

Cited in 2+ publications. This 兔 多克隆 anti-ONECUT1 antibody specifically detects ONECUT1 in WB 和 IHC. The antibody is reactive with 人, 小鼠, 大鼠, 犬, 兔, Cow, Pig, 马 和 斑马鱼 samples.
产品编号 ABIN2780599
发货至: 中国
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Quick Overview for ONECUT1 抗体 (Middle Region) (ABIN2780599)

抗原

See all ONECUT1 抗体
ONECUT1 (One Cut Homeobox 1 (ONECUT1))

适用

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人, 小鼠, 大鼠, 犬, 兔, Cow, Pig, 马, 斑马鱼

宿主

  • 34
  • 1

克隆类型

  • 34
  • 1
多克隆

标记

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This ONECUT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    序列

    ITISQQLGLE LSTVSNFFMN ARRRSLDKWQ DEGSSNSGNS SSSSSTCTKA

    预测反应

    Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

    产品特性

    This is a rabbit polyclonal antibody against ONECUT1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human ONECUT1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 465 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Yuan, Wang, Hu, Tang, Shi, Guo, Song: "Hepatocyte nuclear factor 6 suppresses the migration and invasive growth of lung cancer cells through p53 and the inhibition of epithelial-mesenchymal transition." in: The Journal of biological chemistry, Vol. 288, Issue 43, pp. 31206-16, (2013) (PubMed).

    Huang, Mei, Yu, Zhang, Han, Jiang, Zhou: "Distribution of the interstitial Cajal-like cells in the gallbladder and extrahepatic biliary duct of the guinea-pig." in: Acta histochemica, Vol. 111, Issue 2, pp. 157-65, (2009) (PubMed).

  • 抗原

    ONECUT1 (One Cut Homeobox 1 (ONECUT1))

    别名

    ONECUT1

    背景

    ONECUT1 belongs to the CUT homeobox family. It contains 1 CUT DNA-binding domain and 1 homeobox DNA-binding domain. It is a transcriptional activator. ONECUT1 binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.
    Alias Symbols: HNF-6, HNF6, HNF6A
    Protein Interaction Partner: NR0B2, KAT2B, FOXA2, CREBBP, NR3C1, FOXA1,
    Protein Size: 465

    分子量

    51 kDa

    基因ID

    3175

    NCBI登录号

    NM_004498, NP_004489

    UniProt

    Q9UBC0
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