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RCAN1 抗体 (Middle Region)

Name: RCAN1 抗体 (Middle Region)
SKU: ABIN2780590
Availability: OutOfStock

This anti-RCAN1 antibody is a 兔多克隆 antibody detecting RCAN1 in WB. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 绵羊, 兔和斑马鱼. This Primary Antibody has been cited in 1 publication.

WB Suggested Anti-RCAN1 Antibody Titration: 0. (RCAN1 抗体 (Middle Region))

Image no. 2 for anti-Regulator of Calcineurin 1 (RCAN1) (Middle Region) antibody (ABIN2780590) (RCAN1 抗体 (Middle Region))

Host: Rabbit Target Name: RCAN1 Sample Type: Human Fetal Muscle Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1ug/ml Peptide Concentration: 5ug/ml Lysate Quantity: 25ug/lane/lane Gel Concentration: 0. (RCAN1 抗体 (Middle Region))

WB Suggested Anti-RCAN1 Antibody Positive Control: Lane 1: 20ug Wild type mouse, left ventricle Primary Antibody Dilution : 1:1000 Secondary Antibody : Goat anti rabbit-HRP Secondry Antibody Dilution : 1:5,000 Submitted by: Kathleen Gabrielson (RCAN1 抗体 (Middle Region))

Host: Rabbit Target Name: RCAN1 Sample Tissue: Human HepG2 Whole Cell Antibody Dilution: 1ug/ml (RCAN1 抗体 (Middle Region))

RCAN1 antibody - middle region validated by WB using MOUSE OSTEOCLASTS at 1:1000. (RCAN1 抗体 (Middle Region))

6 images

(1 reference)

产品编号 ABIN2780590

发货至: 中国

Quick Overview for RCAN1 抗体 (Middle Region) (ABIN2780590)

抗原

See all RCAN1 抗体

RCAN1 (Regulator of Calcineurin 1 (RCAN1))

适用

人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 绵羊, 兔, 斑马鱼

宿主

兔

克隆类型

多克隆

标记

This RCAN1 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product RCAN1 Primary Antibody

抗原表位
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Middle Region

序列

PVINYDLLYA ISKLGPGEKY ELHAATDTTP SVVVHVCESD QEKEEEEEME

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 79%

产品特性

This is a rabbit polyclonal antibody against RCAN1. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human RCAN1
anti-Regulator of Calcineurin 1 (RCAN1) (AA 60-245) antibody
RCAN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Regulator of Calcineurin 1 (RCAN1) (AA 1-100) antibody
RCAN1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1B1 unconjugated

anti-Regulator of Calcineurin 1 (RCAN1) antibody
RCAN1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Regulator of Calcineurin 1 (RCAN1) (AA 1-100) antibody
RCAN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G7 unconjugated

anti-Regulator of Calcineurin 1 (RCAN1) (C-Term) antibody
RCAN1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Regulator of Calcineurin 1 (RCAN1) (AA 1-117) antibody
RCAN1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Regulator of Calcineurin 1 (RCAN1) (C-Term) antibody
RCAN1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Regulator of Calcineurin 1 (RCAN1) (AA 41-68), (N-Term) antibody
RCAN1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB36242 unconjugated

anti-Regulator of Calcineurin 1 (RCAN1) (AA 75-104) antibody
RCAN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Regulator of Calcineurin 1 (RCAN1) (AA 222-252) antibody
RCAN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 252 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Voronov, Ochotny, Jaumouillé, Owen, Manolson, Aubin: "The R740S mutation in the V-ATPase a3 subunit increases lysosomal pH, impairs NFATc1 translocation, and decreases in vitro osteoclastogenesis." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 28, Issue 1, pp. 108-18, (2012) (PubMed).
抗原

RCAN1 (Regulator of Calcineurin 1 (RCAN1))

别名

RCAN1

背景

RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.
Alias Symbols: ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1
Protein Interaction Partner: UBC, PPP3CA, NEDD8, APP, FBXW11, BTRC, FBXW4, TOLLIP, TRAF6, IRAK1, HSP90AA1, STAT2, GSK3B, MAP3K3, MAPK3, UXT,
Protein Size: 252

分子量

28 kDa

基因ID

1827

NCBI登录号

NM_004414, NP_004405

UniProt

P53805

途径

Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development