RNF14 抗体 (C-Term)
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北京 101111
Quick Overview for RNF14 抗体 (C-Term) (ABIN2780586)
抗原
See all RNF14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- CMQYFCWICM GSLSRANPYK HFNDPGSPCF NRLFYAVDVD DDIWEDEVED
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预测反应
- Cow: 79%, Dog: 79%, Human: 100%, Rabbit: 79%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against RNF14. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human RNF14
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anti-Ring Finger Protein 14 (RNF14) (AA 217-316) antibody
RNF14 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 4G9 unconjugated
anti-Ring Finger Protein 14 (RNF14) antibodyRNF14 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 14 (RNF14) antibodyRNF14 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4610 unconjugated Recombinant Antibody
anti-Ring Finger Protein 14 (RNF14) (N-Term) antibodyRNF14 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 14 (RNF14) (AA 1-348) antibodyRNF14 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 14 (RNF14) (AA 1-348) antibodyRNF14 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 14 (RNF14) (C-Term) antibodyRNF14 适用: 人, 大鼠, Cow, 犬, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 14 (RNF14) antibodyRNF14 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 14 (RNF14) antibodyRNF14 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Ring Finger Protein 14 (RNF14) (AA 161-210) antibodyRNF14 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 474 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice." in: Cell, Vol. 119, Issue 1, pp. 121-35, (2004) (PubMed).
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: "Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice." in: Cell, Vol. 119, Issue 1, pp. 121-35, (2004) (PubMed).
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- RNF14 (Ring Finger Protein 14 (RNF14))
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别名
- RNF14
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背景
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RNF14 contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
Alias Symbols: ARA54, HFB30, TRIAD2, HRIHFB2038
Protein Interaction Partner: UBE2E2, UBE2D1, DACH1, UBE2D4, LEF1, TCF3, HNF1A, TCF4, CTNNB1, UBC, AR, FAM46A, TNFAIP3, ECT2, UBE2E3, UBE2E1, PHF7, TAGLN, HNRNPA1, VDR, UBE2D3, UBE2D2, UBE2U, UBE2W, UBE2V1, NCOA4, NR3C1, ESR1, RNF14,
Protein Size: 474 -
分子量
- 52 kDa
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基因ID
- 9604
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NCBI登录号
- NM_183401, NP_899648
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UniProt
- Q9UBS8
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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