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RNF14 抗体 (C-Term)

This anti-RNF14 antibody is a 兔 多克隆 antibody detecting RNF14 in WB 和 IHC. Suitable for 人, 大鼠, Cow, 犬 和 兔. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2780586
发货至: 中国

Quick Overview for RNF14 抗体 (C-Term) (ABIN2780586)

抗原

See all RNF14 抗体
RNF14 (Ring Finger Protein 14 (RNF14))

适用

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人, 大鼠, Cow, 犬, 兔

宿主

  • 47
  • 2

克隆类型

  • 45
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多克隆

标记

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This RNF14 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    序列

    CMQYFCWICM GSLSRANPYK HFNDPGSPCF NRLFYAVDVD DDIWEDEVED

    预测反应

    Cow: 79%, Dog: 79%, Human: 100%, Rabbit: 79%, Rat: 79%

    产品特性

    This is a rabbit polyclonal antibody against RNF14. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human RNF14
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 474 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lin, Wu, Tarr, Lindenberg, St-Pierre, Zhang, Mootha, Jäger, Vianna, Reznick, Cui, Manieri, Donovan, Wu, Cooper, Fan, Rohas, Zavacki, Cinti, Shulman, Lowell, Krainc, Spiegelman: "Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice." in: Cell, Vol. 119, Issue 1, pp. 121-35, (2004) (PubMed).

  • 抗原

    RNF14 (Ring Finger Protein 14 (RNF14))

    别名

    RNF14

    背景

    RNF14 contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
    Alias Symbols: ARA54, HFB30, TRIAD2, HRIHFB2038
    Protein Interaction Partner: UBE2E2, UBE2D1, DACH1, UBE2D4, LEF1, TCF3, HNF1A, TCF4, CTNNB1, UBC, AR, FAM46A, TNFAIP3, ECT2, UBE2E3, UBE2E1, PHF7, TAGLN, HNRNPA1, VDR, UBE2D3, UBE2D2, UBE2U, UBE2W, UBE2V1, NCOA4, NR3C1, ESR1, RNF14,
    Protein Size: 474

    分子量

    52 kDa

    基因ID

    9604

    NCBI登录号

    NM_183401, NP_899648

    UniProt

    Q9UBS8

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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