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MED27 抗体 (C-Term)

This anti-MED27 antibody is a 兔 多克隆 antibody detecting MED27 in WB. Suitable for 人, 小鼠, Cow, 犬, 大鼠, 豚鼠, 马, 兔 和 斑马鱼.
产品编号 ABIN2780582
发货至: 中国

Quick Overview for MED27 抗体 (C-Term) (ABIN2780582)

抗原

See all MED27 抗体
MED27 (Mediator Complex Subunit 27 (MED27))

适用

  • 33
  • 15
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, Cow, 犬, 大鼠, 豚鼠, 马, 兔, 斑马鱼

宿主

  • 30
  • 4

克隆类型

  • 32
  • 2
多克隆

标记

  • 20
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MED27 antibody is un-conjugated

应用范围

  • 18
  • 15
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  • 1
Western Blotting (WB)
  • 抗原表位

    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    VVRSFMTWLR SYIKLFQAPC QRCGKFLQDG LPPTWRDFRT LEAFHDTCRQ

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against CRSP8. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human CRSP8
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 311 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MED27 (Mediator Complex Subunit 27 (MED27))

    别名

    CRSP8

    背景

    He activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. CRSP8 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. CRSP8 is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
    Alias Symbols: CRSP8, CRAP34, CRSP34, TRAP37
    Protein Interaction Partner: UBC, CDK19, CDK8, MED19, ARFGAP1, MED26, SOX5, POLR2C, RBPJ, AFP, FBXW7, EPAS1, MED4, MED12, MED14, MED1, MED28, OBFC1, MED18, ZC3H13, QKI, TRIP4, TADA2A, MED9, MED30, MED8, MED22, MED10, MED29,
    Protein Size: 311

    分子量

    35 kDa

    基因ID

    9442

    NCBI登录号

    NM_004269, NP_004260

    UniProt

    Q6P2C8

    途径

    Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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