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COPS2 抗体 (N-Term)

This anti-COPS2 antibody is a 兔 多克隆 antibody detecting COPS2 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, 豚鼠 和 兔. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2780578
发货至: 中国

Quick Overview for COPS2 抗体 (N-Term) (ABIN2780578)

抗原

See all COPS2 抗体
COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))

适用

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人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 马, 豚鼠, 兔

宿主

  • 52
  • 2
  • 1

克隆类型

  • 53
  • 2
多克隆

标记

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This COPS2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 6
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    N-Term

    序列

    MSDMEDDFMC DDEEDYDLEY SEDSNSEPNV DLENQYYNSK ALKEDDPKAA

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against COPS2. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human COPS2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 443 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Pick, Golan, Zimbler, Guo, Sharaby, Tsuge, Hofmann, Wei: "The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain." in: PLoS ONE, Vol. 7, Issue 8, pp. e43980, (2012) (PubMed).

  • 抗原

    COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))

    别名

    COPS2

    背景

    COPS2 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. COPS2 is also innvolved in early stage of neuronal differentiation via its interaction with NIF3L1.
    Alias Symbols: ALIEN, CSN2, SGN2, TRIP15
    Protein Interaction Partner: UBC, GPS1, Map3k10, 5830415F09Rik, Taf1b, EP300, Crebbp, cul1, COPS7B, EPB41L1, COPS5, FBXW4, SENP8, vpr, IRF5, COPS4, COPS7A, COPS6, COPS8, COPS3, PMPCA, SEPHS1, EHBP1L1, SLAIN2, GAPVD1, PFKFB2, SEPT2, IRS2, GRK5, DDB2, LRR1, DCAF11, DDA1, RFWD2, DCAF8,
    Protein Size: 443

    分子量

    51 kDa

    基因ID

    9318

    NCBI登录号

    NM_004236, NP_004227

    UniProt

    P61203

    途径

    Cell Division Cycle
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