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KLF4 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects KLF4 in WB 和 IHC. It exhibits reactivity toward 人, 小鼠, 大鼠, Cow, 马, 犬, 兔, 豚鼠 和 斑马鱼.It has been mentioned in 1 publication
产品编号 ABIN2780577
发货至: 中国
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Quick Overview for KLF4 抗体 (C-Term) (ABIN2780577)

抗原

See all KLF4 抗体
KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

适用

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人, 小鼠, 大鼠, Cow, 马, 犬, 兔, 豚鼠, 斑马鱼

宿主

  • 97
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  • 1

克隆类型

  • 75
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多克隆

标记

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This KLF4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    序列

    AGCGKTYTKS SHLKAHLRTH TGEKPYHCDW DGCGWKFARS DELTRHYRKH

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against KLF4. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human KLF4
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 470 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Natesampillai, Kerkvliet, Leung, Veldhuis: "Regulation of Kruppel-like factor 4, 9, and 13 genes and the steroidogenic genes LDLR, StAR, and CYP11A in ovarian granulosa cells." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 2, pp. E385-91, (2008) (PubMed).

  • 抗原

    KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

    别名

    KLF4

    背景

    The mammalian Kruppel-like transcription factor, KLF4 is involved in preventing centrosome amplification following DNA damage caused by gamma-irradiation. It is both necessary and sufficient in preventing centrosome amplification following gamma-radiation-induced DNA damage and does so by transcriptionally suppressing cyclin E expression n. Kruppel-like factor 4 is also known to exhibit checkpoint function during the G1/S and G2/M transitions of the cell cycle.
    Alias Symbols: EZF, GKLF
    Protein Interaction Partner: EP300, CREBBP, SETD7, CTBP1, Dlg4, APP, CUL2, VHL, UBC, TCEB2, SP1, RELA, PRKCD, PPARG, SMARCA4, HDAC2, HDAC7, KAT5, HDAC1, HDAC5, ELK1, KLF6, TP53,
    Protein Size: 470

    分子量

    50 kDa

    基因ID

    9314

    NCBI登录号

    NM_004235, NP_004226

    UniProt

    O43474

    途径

    Peptide Hormone Metabolism, Stem Cell Maintenance
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