E2F2 抗体 (Middle Region)
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Quick Overview for E2F2 抗体 (Middle Region) (ABIN2780568)
抗原
See all E2F2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- DQFLSPTLAC SSPLISFSPS LDQDDYLWGL EAGEGISDLF DSYDLGDLLI
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预测反应
- Cow: 92%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 75%
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产品特性
- This is a rabbit polyclonal antibody against E2F2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human E2F2
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anti-E2F Transcription Factor 2 (E2F2) (AA 1-83) antibody
E2F2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) antibodyE2F2 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB5250 unconjugated Recombinant Antibody
anti-E2F Transcription Factor 2 (E2F2) (AA 1-437) antibodyE2F2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) (Internal Region) antibodyE2F2 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) (AA 191-240) antibodyE2F2 适用: 人, 小鼠, 兔, 犬, Cow, 马, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) antibodyE2F2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) (AA 1-110) antibodyE2F2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) (C-Term) antibodyE2F2 适用: 人, 小鼠, 兔, 犬, 马, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) (Internal Region) antibodyE2F2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 2 (E2F2) (AA 1-83) antibodyE2F2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 437 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- E2F2 (E2F Transcription Factor 2 (E2F2))
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别名
- E2F2
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背景
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E2F2 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46 % amino acid identity to E2F1.The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46 % amino acid identity to E2F1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: E2F-2
Protein Interaction Partner: RB1, GNB5, GIT2, TFDP1, RBL1, ARID3A, ELAVL1, ATAD2, KMT2D, KMT2A, RYBP, SETD8, BCAR1, TFDP2, BRD2, YY1, SP1, CDK3, RNF144A, FHL2, SPIB, RBL2, E2F4, MYBL2, EAPP, TP53BP2, PPP1R13B, TP53INP1, JMY, GAB2, CDC25A, CDC6, E2F1, UXT, MT1G,
Protein Size: 437 -
分子量
- 47 kDa
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基因ID
- 1870
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NCBI登录号
- NM_004091, NP_004082
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UniProt
- Q14209
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication
抗原
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