SAP30 抗体 (N-Term)
Quick Overview for SAP30 抗体 (N-Term) (ABIN2780555)
抗原
See all SAP30 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MNGFTPDEMS RGGDAAAAVA AVVAAAAAAA SAGNGTGAGT GAEVPGAGAV
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预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against SAP30. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SAP30
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anti-Sin3A-Associated Protein, 30kDa (SAP30) (AA 131-219) antibody
SAP30 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4D2 unconjugated
anti-Sin3A-Associated Protein, 30kDa (SAP30) (AA 1-220) antibodySAP30 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Sin3A-Associated Protein, 30kDa (SAP30) (AA 151-200) antibodySAP30 适用: 人, 小鼠, 兔, Cow, 大鼠, 豚鼠, 马, Pig, 猴, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Sin3A-Associated Protein, 30kDa (SAP30) (N-Term) antibodySAP30 适用: 人, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Sin3A-Associated Protein, 30kDa (SAP30) (AA 1-220) antibodySAP30 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sin3A-Associated Protein, 30kDa (SAP30) (AA 131-219) antibodySAP30 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D3 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 220 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))
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别名
- SAP30
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背景
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Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP30 is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3.
Protein Interaction Partner: HDAC3, CUL4B, DDB1, HDAC1, SIN3A, UBC, HDAC2, BRMS1L, ING1, ARID4A, SAMSN1, ZNF395, UBASH3B, RBBP7, RBBP4, CHD4, ALL1, TAF6, SMARCA2, SAP25, RBP1, HIST2H2BE, PCBD1, ID3, SAP30BP, HIST2H4A, HBP1, HIST1H2AL, BRMS1, CIR1, HIST3H3, NCOR1, NCOR2, MXD1, YY1, HT
Protein Size: 220 -
分子量
- 23 kDa
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基因ID
- 8819
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NCBI登录号
- NM_003864, NP_003855
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UniProt
- O75446
抗原
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