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ZFP36 抗体 (Middle Region)

The 兔 多克隆 anti-ZFP36 antibody is suitable to detect ZFP36 in samples from 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔 和 绵羊. It has been validated for WB 和 IHC.
产品编号 ABIN2780505
发货至: 中国
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Quick Overview for ZFP36 抗体 (Middle Region) (ABIN2780505)

抗原

See all ZFP36 抗体
ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 绵羊

宿主

  • 36
  • 5

克隆类型

  • 36
  • 5
多克隆

标记

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This ZFP36 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    序列

    PSCRRATPIS VWGPLGGLVR TPSVQSLGSD PDEYASSGSS LGGSDSPVFE

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Sheep: 100%

    产品特性

    This is a rabbit polyclonal antibody against ZFP36. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human ZFP36
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 326 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    ZFP36 (Zinc Finger Protein 36, C3H Type, Homolog (Mouse) (ZFP36))

    别名

    ZFP36

    背景

    ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Knockdown of ZFP36 increased both cognate macrophage gene mRNAs and inflammatory tumor necrosis factor protein release. Overexpression of ZFP36 resulted in decreased levels of the same genes supporting its role in regulating macrophage gene expression. Multiple phosphorylation sites in ZFP36 in mammalian cells were reported. ZFP36 can be phosphorylated by JNK as well as by the other members of the greater MAP kinase family. Gene expression profiling predicts clinical outcome of prostate cancer. Inappropriate ZFP36 production may be one factor that contributes to higher rheumatoid arthritis disease activity.
    Alias Symbols: G0S24, GOS24, NUP475, RNF162A, TIS11, TTP
    Protein Interaction Partner: YWHAB, PPP2CA, DNAJB1, DCP1B, DHX36, PRR5L, XRN1, UBC, TRAF2, EXOSC6, UPF2, EXOSC8, YWHAQ, TNF, DCP2, EDC3, DCP1A, EDC4, CDK6, APP, LIN28A, SH3KBP1, PABPC1, NCL, MAP3K4, HSPA4, HDAC7, HDAC3, NFKB1, HOXC9, HDAC1, CCDC85B, MAPKAPK2, YWHAG, SFN, HMGB1, NUP21
    Protein Size: 326

    分子量

    34 kDa

    基因ID

    7538

    NCBI登录号

    NM_003407, NP_003398

    UniProt

    P26651
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