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STAT6 抗体 (C-Term)

Name: STAT6 抗体 (C-Term)
SKU: ABIN2780481
Availability: OutOfStock

This anti-STAT6 antibody is a 兔多克隆 antibody detecting STAT6 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 兔, 马和豚鼠.

WB Suggested Anti-STAT6 Antibody Titration: 0. (STAT6 抗体 (C-Term))

Immunohistochemistry (IHC) image for anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (C-Term) antibody (ABIN2780481) (STAT6 抗体 (C-Term))

IHC

2 images

产品编号 ABIN2780481

发货至: 中国

Quick Overview for STAT6 抗体 (C-Term) (ABIN2780481)

抗原

See all STAT6 抗体

STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))

适用

人, 小鼠, 大鼠, 犬, Cow, 兔, 马, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This STAT6 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product STAT6 Primary Antibody

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C-Term

序列

TEQDLTKLLL EGQGESGGGS LGAQPLLQPS HYGQSGISMS HMDLRANPSW

预测反应

Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

产品特性

This is a rabbit polyclonal antibody against STAT6. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the C terminal region of human STAT6
anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (AA 694-801) antibody
STAT6 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 6C10 unconjugated

anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (AA 614-663) antibody
STAT6 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 猴, Pig, 马, 豚鼠, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (pThr645) antibody
STAT6 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (AA 1-180) antibody
STAT6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (C-Term) antibody
STAT6 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (pTyr641) antibody
STAT6 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) antibody
STAT6 适用: 人, 小鼠 WB, IHC, IHC (p), IF (cc), FACS 宿主: 兔 Monoclonal 9A7 unconjugated

anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (AA 557-841) antibody
STAT6 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (AA 1-847) antibody
STAT6 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6) (AA 694-801) antibody
STAT6 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G7 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 847 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))

别名

STAT6

背景

STAT6 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.
Alias Symbols: D12S1644, IL-4-STAT, STAT6B, STAT6C
Protein Interaction Partner: UBC, IRF4, PDE12, EHD1, USP8, API5, PGGT1B, EP300, TRIM28, JAK3, RCN3, LITAF, IL4R, EEF1A1, VKORC1, PTPN2, STAT2, JAK1, IFNG, IFNAR1, SRXN1, PSAT1, DSTN, SEC24A, AHCYL1, SSSCA1, NUBP2, SH3BGRL, RAD23B, PPM1G, IGBP1, CEBPE, SND1, SUMO2, FCER2, SFPQ, IGHE,
Protein Size: 847

分子量

94 kDa

基因ID

6778

NCBI登录号

NM_003153, NP_003144

UniProt

P42226

途径

JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response