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IRF4 抗体 (Middle Region)

This 兔 多克隆 antibody specifically detects IRF4 in WB. It exhibits reactivity toward 人, 大鼠, 犬, 豚鼠 和 马.It has been mentioned in 1 publication
产品编号 ABIN501643
发货至: 中国
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Quick Overview for IRF4 抗体 (Middle Region) (ABIN501643)

抗原

See all IRF4 抗体
IRF4 (Interferon Regulatory Factor 4 (IRF4))

适用

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人, 大鼠, 犬, 豚鼠, 马

宿主

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克隆类型

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多克隆

标记

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This IRF4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    TAHVEPLLAR QLYYFAQQNS GHFLRGYDLP EHISNPEDYH RSIRHSSIQE

    预测反应

    Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against IRF4. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human IRF4
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 451 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Han, Kraft, Nan, Guo, Chen, Qureshi, Hankinson, Hu, Duffy, Zhao, Martin, Montgomery, Hayward, Thomas, Hoover, Chanock, Hunter: "A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation." in: PLoS genetics, Vol. 4, Issue 5, pp. e1000074, (2008) (PubMed).

  • 抗原

    IRF4 (Interferon Regulatory Factor 4 (IRF4))

    别名

    IRF4

    背景

    IRF4 is a transcriptional activator. It binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter.It also binds the immunoglobulin lambda light chain enhancer, together with PU.1. IRF4 probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells.
    Alias Symbols: LSIRF, MUM1, NF-EM5
    Protein Interaction Partner: UBC, STAT6, BCL6, TOP1, IRAK1, PRRC2B, YTHDC2, VPS35, PEG10, TLK2, CARM1, IKBKAP, ETV7, BATF, HOXB13, PROX1, HOXC11, FKBP4, SPIB, PRDM1, MYD88, TRAF2, NFATC2, SPI1,
    Protein Size: 451

    分子量

    52 kDa

    基因ID

    3662

    NCBI登录号

    NM_002460, NP_002451

    UniProt

    Q15306

    途径

    Chromatin Binding
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