Msx2/Hox8 抗体 (N-Term)
Quick Overview for Msx2/Hox8 抗体 (N-Term) (ABIN2780427)
抗原
See all Msx2/Hox8 (Msx2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MASPSKGNDL FSPDEEGPAV VAGPGPGPGG AEGAAEERRV KVSSLPFSVE
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预测反应
- Cow: 100%, Dog: 100%, Goat: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against MSX2. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MSX2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 267 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Msx2/Hox8 (Msx2) (Msh Momeobox 2 (Msx2))
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别名
- MSX2
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背景
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MSX2 is a member of the muscle segment homeobox gene family. The protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
Alias Symbols: FPP, MSH, PFM, CRS2, HOX8, PFM1
Protein Interaction Partner: ATXN1, PIAS2, UBC, XRCC5, XRCC6, ZDHHC2, TLE2, TLE1, PPARG, POU2AF1, NR3C1, POLR3D, SPEN, ZBTB17, RUNX2, DLX5, MAGED1, GTF2F2, GTF2F1, MSX1, DLX2, MSX2, CEBPA, PITX2,
Protein Size: 267 -
分子量
- 29 kDa
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基因ID
- 4488
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NCBI登录号
- NM_002449, NP_002440
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UniProt
- P35548
抗原
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